Cargando…

Integrin α10-Antibodies Reduce Glioblastoma Tumor Growth and Cell Migration

SIMPLE SUMMARY: Glioblastoma (GB) is the most common and most deadly form of brain tumor in adults which currently lacks effective treatments. Thus, there is a high need to identify new and effective ways to target the aggressive GB cells and treat the GB patients. In this study, we investigated the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Masoumi, Katarzyna Chmielarska, Huang, Xiaoli, Sime, Wondossen, Mirkov, Anna, Munksgaard Thorén, Matilda, Massoumi, Ramin, Lundgren-Åkerlund, Evy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7980568/ https://www.ncbi.nlm.nih.gov/pubmed/33803359 http://dx.doi.org/10.3390/cancers13051184

Ejemplares similares

Integrin α10, a Novel Therapeutic Target in Glioblastoma, Regulates Cell Migration, Proliferation, and Survival
por: Munksgaard Thorén, Matilda, et al.
Publicado: (2019)

NLK-mediated phosphorylation of HDAC1 negatively regulates Wnt signaling
por: Masoumi, Katarzyna Chmielarska, et al.
Publicado: (2017)

CYLD and SUMO in neuroblastoma therapy
por: Masoumi, Katarzyna Chmielarska, et al.
Publicado: (2016)

BAP1 induces cell death via interaction with 14-3-3 in neuroblastoma
por: Sime, Wondossen, et al.
Publicado: (2018)

Integrin α2β1 Is a Receptor for the Cartilage Matrix Protein Chondroadherin
por: Camper, Lisbet, et al.
Publicado: (1997)

Expression of Integrin Alpha10 Is Induced in Malignant Melanoma
por: Wenke, Ann-Kathrin, et al.
Publicado: (2007)

Early diagnostic value of Bcl-3 localization in colorectal cancer
por: Saamarthy, Karunakar, et al.
Publicado: (2015)

Nemo-like kinase regulates the expression of vascular endothelial growth factor (VEGF) in alveolar epithelial cells
por: Ke, Hengning, et al.
Publicado: (2016)

Association of Nuclear-Localized Nemo-Like Kinase with Heat-Shock Protein 27 Inhibits Apoptosis in Human Breast Cancer Cells
por: Shaw-Hallgren, Gina, et al.
Publicado: (2014)

Human integrin α10β1-selected mesenchymal stem cells home to cartilage defects in the rabbit knee and assume a chondrocyte-like phenotype
por: Andersen, Camilla, et al.
Publicado: (2022)

Inhibition of mitotic kinase Mps1 promotes cell death in neuroblastoma
por: Simon Serrano, Sonia, et al.
Publicado: (2020)

Integrin α10β1-selected mesenchymal stem cells reduced hypercoagulopathy in a porcine model of acute respiratory distress syndrome
por: Edström, Dag, et al.
Publicado: (2023)

Temporal extracellular vesicle protein changes following intraarticular treatment with integrin α10β1-selected mesenchymal stem cells in equine osteoarthritis
por: Clarke, Emily J., et al.
Publicado: (2022)

Gene Expression Signature of Acquired Chemoresistance in Neuroblastoma Cells
por: Jemaà, Mohamed, et al.
Publicado: (2020)

Novel Cyclophilin Inhibitor Decreases Cell Proliferation and Tumor Growth in Models of Hepatocellular Carcinoma
por: Simón Serrano, Sonia, et al.
Publicado: (2021)

Discovery of epi-Enprioline as a Novel Drug for the Treatment of Vincristine Resistant Neuroblastoma
por: Sime, Wondossen, et al.
Publicado: (2020)

High expression of CD34 and α6-integrin contributes to the cancer-initiating cell behaviour in ultraviolet-induced mouse skin squamous cell carcinoma
por: Ke, Hengning, et al.
Publicado: (2020)

CYLD negatively regulates cell-cycle progression by inactivating HDAC6 and increasing the levels of acetylated tubulin
por: Wickström, Sara A, et al.
Publicado: (2010)

Tumor Suppressor Function of CYLD in Nonmelanoma Skin Cancer
por: Masoumi, K. C., et al.
Publicado: (2011)

Myc-induced glutaminolysis bypasses HIF-driven glycolysis in hypoxic small cell lung carcinoma cells
por: Thorén, Matilda Munksgaard, et al.
Publicado: (2017)

αV-Integrin-Dependent Inhibition of Glioblastoma Cell Migration, Invasion and Vasculogenic Mimicry by the uPAcyclin Decapeptide
por: Franco, Paola, et al.
Publicado: (2023)

Molecular characterization of protein kinase C delta (PKCδ)-Smac interactions
por: Holmgren, Christian, et al.
Publicado: (2016)

PLK1 as a cooperating partner for BCL2-mediated antiapoptotic program in leukemia
por: Shah, Kinjal, et al.
Publicado: (2023)

Goldilocks and the Three Trials: Clinical Trials Targeting the α(v)β(6) Integrin in Idiopathic Pulmonary Fibrosis
por: Sime, Patricia, et al.
Publicado: (2022)

Temozolomide-Acquired Resistance Is Associated with Modulation of the Integrin Repertoire in Glioblastoma, Impact of α5β1 Integrin
por: Sani, Saidu, et al.
Publicado: (2022)

CysLT(1)R Antagonists Inhibit Tumor Growth in a Xenograft Model of Colon Cancer
por: Savari, Sayeh, et al.
Publicado: (2013)

α(6) Integrins Are Required for Langerhans Cell Migration from the Epidermis
por: Price, Abigail A., et al.
Publicado: (1997)

Integrin-αvβ3 as a Therapeutic Target in Glioblastoma: Back to the Future?
por: Echavidre, William, et al.
Publicado: (2022)

Treatment of osteoarthritis using a helper-dependent adenoviral vector retargeted to chondrocytes
por: Ruan, Merry ZC, et al.
Publicado: (2016)

Reversine inhibits Colon Carcinoma Cell Migration by Targeting JNK1
por: Jemaà, Mohamed, et al.
Publicado: (2018)

Glioblastoma cells use an integrin- and CD44-mediated motor-clutch mode of migration in brain tissue
por: Anderson, Sarah M, et al.
Publicado: (2023)

Olfactory Ensheathing Cells Express α7 Integrin to Mediate Their Migration on Laminin
por: Ingram, Norianne T., et al.
Publicado: (2016)

CD47 Regulates Collagen I-Induced Cyclooxygenase-2 Expression and Intestinal Epithelial Cell Migration
por: Broom, Oliver Jay, et al.
Publicado: (2009)

RNA Aptamers Targeting Integrin α5β1 as Probes for Cyto- and Histofluorescence in Glioblastoma
por: Fechter, Pierre, et al.
Publicado: (2019)

Ligand-Induced Tyrosine Phosphorylation of Cysteinyl Leukotriene Receptor 1 Triggers Internalization and Signaling in Intestinal Epithelial Cells
por: Parhamifar, Ladan, et al.
Publicado: (2010)

Regulation and Role of αE Integrin and Gut Homing Integrins in Migration and Retention of Intestinal Lymphocytes during Inflammatory Bowel Disease
por: Keir, Mary E., et al.
Publicado: (2021)

Integrins control migration style
por: Tuma, Rabiya S.
Publicado: (2005)

Diacylglycerol kinase α controls RCP-dependent integrin trafficking to promote invasive migration
por: Rainero, Elena, et al.
Publicado: (2012)

β1-integrin-dependent migration of microglia in response to neuron-released α-synuclein
por: Kim, Changyoun, et al.
Publicado: (2014)

Tetraspanin 8-Rictor-Integrin α3 Complex Is Required for Glioma Cell Migration
por: Pan, Si-Jian, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_7rs6d2ruuro8qqs62jc1v0ubev