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Opioid therapy vs. multimodal analgesia in head and neck Cancer (OPTIMAL-HN): study protocol for a randomized clinical trial
BACKGROUND: Radiation-induced mucositis (RIM) pain confers substantial morbidity for head and neck cancer (HNC) patients undergoing radiotherapy alone (RT) or chemoradiotherapy (CRT), often reducing treatment compliance. However, no standard currently exists for the treatment of RIM, and high dose o...
Autores principales: | Zayed, Sondos, Lang, Pencilla, Mendez, Lucas C., Read, Nancy, Sathya, Jinka, Venkatesan, Varagur, Moulin, Dwight E., Warner, Andrew, Palma, David A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7980584/ https://www.ncbi.nlm.nih.gov/pubmed/33740977 http://dx.doi.org/10.1186/s12904-021-00735-0 |
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