Non-targeted proteomics of acute respiratory distress syndrome: clinical and research applications

Acute respiratory distress syndrome (ARDS) is characterized by refractory hypoxemia caused by accumulation of pulmonary fluid with a high mortality rate, but the underlying mechanism is not yet fully understood, causing absent specific therapeutic drugs to treat with ARDS. In recent years, more and...

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Autores principales: Wen, Xu-Peng, Zhang, Yue-Zhong, Wan, Qi-Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7980750/
https://www.ncbi.nlm.nih.gov/pubmed/33743690
http://dx.doi.org/10.1186/s12953-021-00174-y
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author Wen, Xu-Peng
Zhang, Yue-Zhong
Wan, Qi-Quan
author_facet Wen, Xu-Peng
Zhang, Yue-Zhong
Wan, Qi-Quan
author_sort Wen, Xu-Peng
collection PubMed
description Acute respiratory distress syndrome (ARDS) is characterized by refractory hypoxemia caused by accumulation of pulmonary fluid with a high mortality rate, but the underlying mechanism is not yet fully understood, causing absent specific therapeutic drugs to treat with ARDS. In recent years, more and more studies have applied proteomics to ARDS. Non-targeted studies of proteomics in ARDS are just beginning and have the potential to identify novel drug targets and key pathways in this disease. This paper will provide a brief review of the recent advances in the application of non-targeted proteomics to ARDS.
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spelling pubmed-79807502021-03-22 Non-targeted proteomics of acute respiratory distress syndrome: clinical and research applications Wen, Xu-Peng Zhang, Yue-Zhong Wan, Qi-Quan Proteome Sci Review Acute respiratory distress syndrome (ARDS) is characterized by refractory hypoxemia caused by accumulation of pulmonary fluid with a high mortality rate, but the underlying mechanism is not yet fully understood, causing absent specific therapeutic drugs to treat with ARDS. In recent years, more and more studies have applied proteomics to ARDS. Non-targeted studies of proteomics in ARDS are just beginning and have the potential to identify novel drug targets and key pathways in this disease. This paper will provide a brief review of the recent advances in the application of non-targeted proteomics to ARDS. BioMed Central 2021-03-20 /pmc/articles/PMC7980750/ /pubmed/33743690 http://dx.doi.org/10.1186/s12953-021-00174-y Text en © The Author(s) 2021 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Review
Wen, Xu-Peng
Zhang, Yue-Zhong
Wan, Qi-Quan
Non-targeted proteomics of acute respiratory distress syndrome: clinical and research applications
title Non-targeted proteomics of acute respiratory distress syndrome: clinical and research applications
title_full Non-targeted proteomics of acute respiratory distress syndrome: clinical and research applications
title_fullStr Non-targeted proteomics of acute respiratory distress syndrome: clinical and research applications
title_full_unstemmed Non-targeted proteomics of acute respiratory distress syndrome: clinical and research applications
title_short Non-targeted proteomics of acute respiratory distress syndrome: clinical and research applications
title_sort non-targeted proteomics of acute respiratory distress syndrome: clinical and research applications
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7980750/
https://www.ncbi.nlm.nih.gov/pubmed/33743690
http://dx.doi.org/10.1186/s12953-021-00174-y
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