Cargando…

CD95L and Anti-Tumor Immune Response: Current Understanding and New Evidence

The ability of FasL/CD95L to induce apoptosis in various Fas/CD95-expressing cells has been described in the context of hematopoiesis or thymic elimination of self-reactive T cells and resolution of an acute immune response under physiological conditions. At the same time, non-apoptotic CD95 activat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Richards, David M, Merz, Christian, Gieffers, Christian, Krendyukov, Andriy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Perspectives
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7981134/ https://www.ncbi.nlm.nih.gov/pubmed/33758545 http://dx.doi.org/10.2147/CMAR.S297499

Ejemplares similares

Asunercept as an innovative therapeutic approach for recurrent glioblastoma and other malignancies
por: Krendyukov, Andriy, et al.
Publicado: (2019)

Neutralization of the CD95 ligand by APG101 inhibits invasion of glioma cells in vitro
por: Merz, Christian, et al.
Publicado: (2015)

A Single-Chain-Based Hexavalent CD27 Agonist Enhances T Cell Activation and Induces Anti-Tumor Immunity
por: Thiemann, Meinolf, et al.
Publicado: (2018)

Concepts for agonistic targeting of CD40 in immuno-oncology
por: Richards, David M., et al.
Publicado: (2019)

The CD40 agonist HERA-CD40L results in enhanced activation of antigen presenting cells, promoting an anti-tumor effect alone and in combination with radiotherapy
por: Frankish, Jamie, et al.
Publicado: (2023)

The CD95/CD95L Signaling Pathway: A Role in Carcinogenesis
por: Fouqué, Amélie, et al.
Publicado: (2014)

The CD95/CD95L Signaling Pathway: A Role in Carcinogenesis
por: Fouqué, Amélie, et al.
Publicado: (2020)

The dual role of the CD95 and CD95L signaling pathway in glioblastoma
por: Zhang, Yanrui, et al.
Publicado: (2022)

Modulation of the CD95-Induced Apoptosis: The Role of CD95 N-Glycosylation
por: Shatnyeva, Olga M., et al.
Publicado: (2011)

Therapeutic approaches targeting CD95L/CD95 signaling in cancer and autoimmune diseases
por: Risso, Vesna, et al.
Publicado: (2022)

HERA-GITRL activates T cells and promotes anti-tumor efficacy independent of FcγR-binding functionality
por: Richards, David M., et al.
Publicado: (2019)

Neddylation and anti-tumor immunity
por: Wang, Xiaoguang, et al.
Publicado: (2021)

Trigeminal neuralgia causes neurodegeneration in rats associated with upregulation of the CD95/CD95L pathway
por: Wang, Lu, et al.
Publicado: (2020)

The role of CD95 and CD95 ligand in cancer
por: Peter, M E, et al.
Publicado: (2015)

Clinical Response to the CD95-Ligand Inhibitor Asunercept Is Defined by a Pro-Inflammatory Serum Cytokine Profile
por: Radujkovic, Aleksandar, et al.
Publicado: (2020)

CD95 promotes metastatic spread via Sck in pancreatic ductal adenocarcinoma
por: Teodorczyk, M, et al.
Publicado: (2015)

Current understanding of the bi-directional relationship of major depression with inflammation
por: Messay, Berhane, et al.
Publicado: (2012)

Attaining 95-95-95 through Implementation Science: 15 Years of Insights and Best Practices from the Walter Reed Army Institute of Research’s Implementation of the U.S. President’s Emergency Plan for AIDS Relief
por: Lee, Elizabeth H., et al.
Publicado: (2021)

Pro- and anti-apoptotic CD95 signaling in T cells
por: Paulsen, Maren, et al.
Publicado: (2011)

The abscopal effect of anti-CD95 and radiotherapy in melanoma
por: Xu, Jixiang, et al.
Publicado: (2023)

Early Access Provision for Innovative Medicinal Products in Oncology: Challenges and Opportunities
por: Krendyukov, Andriy
Publicado: (2020)

Innovative oncology products: time to revisit the strategy development?
por: Krendyukov, Andriy
Publicado: (2019)

CD95 maintains stem cell-like and non-classical EMT programs in primary human glioblastoma cells
por: Drachsler, M, et al.
Publicado: (2016)

CD95L Inhibition Impacts Gemcitabine-Mediated Effects and Non-Apoptotic Signaling of TNF-α and TRAIL in Pancreatic Tumor Cells
por: Rashid, Khalid, et al.
Publicado: (2021)

About the Need for a More Adequate Way to Get an Understanding of the Experiencing of Aesthetic Items
por: Carbon, Claus-Christian
Publicado: (2023)

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
por: Torres, Angeli Eloise, et al.
Publicado: (2020)

HIF-1α Inhibition Improves Anti-Tumor Immunity and Promotes the Efficacy of Stereotactic Ablative Radiotherapy (SABR)
por: Song, Chang W., et al.
Publicado: (2022)

Sterilization of N95 respirators: The time for action is upon us!
por: Prakash, Arjun, et al.
Publicado: (2020)

Seeing is believing: anti-PD-1/PD-L1 monoclonal antibodies in action for checkpoint blockade tumor immunotherapy
por: Tan, Shuguang, et al.
Publicado: (2016)

CD95/Fas suppresses NF-κB activation through recruitment of KPC2 in a CD95L/FasL-independent mechanism
por: Guégan, Jean-Philippe, et al.
Publicado: (2021)

COVID toes: where do we stand with the current evidence?
por: Baeck, Marie, et al.
Publicado: (2021)

Cosmetic labiaplasty on minors: a review of current trends and evidence
por: Kalampalikis, Andreas, et al.
Publicado: (2021)

Understanding Evidence-Based Practice (EBP) Implementation in HCOs Through the Lens of Organizational Theory
por: Rangachari, Pavani
Publicado: (2020)

CD40L/CD40 bidirectional signaling is a major regulator of neuronal morphology in the developing nervous system
por: Carriba, Paulina, et al.
Publicado: (2021)

CD137L, a driver of harmful inflammation in the nervous system
por: Wong, Hiu Yi, et al.
Publicado: (2023)

The many faces of the anti-COVID immune response
por: Vardhana, Santosha A., et al.
Publicado: (2020)

Extrapolation concept at work with biosimilar: a decade of experience in oncology
por: Krendyukov, Andriy, et al.
Publicado: (2018)

The ESMO position paper on biosimilars in oncology: enhancing the provision of accurate education and information
por: Schiestl, Martin, et al.
Publicado: (2017)

Epoetin Biosimilars in the Treatment of Renal Anemia: What Have We Learned from a Decade of European Experience?
por: Goldsmith, David, et al.
Publicado: (2018)

Ultraviolet Light Induces Apoptosis via Direct Activation of CD95 (Fas/APO-1) Independently of Its Ligand CD95L
por: Aragane, Yoshinori, et al.
Publicado: (1998)

Cannot write session to /tmp/vufind_sessions/sess_m8at24b13334eklkp82nm6pgg1