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Challenges Involved in Incorporating Personalised Treatment Plan as Routine Care of Patients with Diabetes

Diabetes is a heterogenous disorder, and patients with this disorder vary considerably in their clinical presentation, response to therapy and risk of complications. Expanding knowledge about the pathophysiology of various forms of diabetes has raised the possibility that diagnostic and therapeutic...

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Autores principales: Unnikrishnan, Ranjit, Radha, Venkatesan, Mohan, Viswanathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7981142/
https://www.ncbi.nlm.nih.gov/pubmed/33758531
http://dx.doi.org/10.2147/PGPM.S271582
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author Unnikrishnan, Ranjit
Radha, Venkatesan
Mohan, Viswanathan
author_facet Unnikrishnan, Ranjit
Radha, Venkatesan
Mohan, Viswanathan
author_sort Unnikrishnan, Ranjit
collection PubMed
description Diabetes is a heterogenous disorder, and patients with this disorder vary considerably in their clinical presentation, response to therapy and risk of complications. Expanding knowledge about the pathophysiology of various forms of diabetes has raised the possibility that diagnostic and therapeutic modalities can be tailored to the individual patient in a personalized manner. The recent publication of a Consensus Statement on precision diabetes care underlines the major strides made in this field in the recent past. However, while personalized diabetes care has the potential to significantly improve outcomes in patients with diabetes in a safe and cost-effective manner, its wider application presents several challenges, especially in resource-strained settings. These challenges pertain equally to precision diagnostics, precision therapeutics and precision monitoring. This article discusses some of the important challenges that care providers are likely to face in applying the personalized approach in caring for their patients with diabetes, in the context of diagnosis and management of type 1 diabetes, type 2 diabetes and monogenic forms of diabetes. Suggestions are also presented for overcoming some of these challenges.
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spelling pubmed-79811422021-03-22 Challenges Involved in Incorporating Personalised Treatment Plan as Routine Care of Patients with Diabetes Unnikrishnan, Ranjit Radha, Venkatesan Mohan, Viswanathan Pharmgenomics Pers Med Review Diabetes is a heterogenous disorder, and patients with this disorder vary considerably in their clinical presentation, response to therapy and risk of complications. Expanding knowledge about the pathophysiology of various forms of diabetes has raised the possibility that diagnostic and therapeutic modalities can be tailored to the individual patient in a personalized manner. The recent publication of a Consensus Statement on precision diabetes care underlines the major strides made in this field in the recent past. However, while personalized diabetes care has the potential to significantly improve outcomes in patients with diabetes in a safe and cost-effective manner, its wider application presents several challenges, especially in resource-strained settings. These challenges pertain equally to precision diagnostics, precision therapeutics and precision monitoring. This article discusses some of the important challenges that care providers are likely to face in applying the personalized approach in caring for their patients with diabetes, in the context of diagnosis and management of type 1 diabetes, type 2 diabetes and monogenic forms of diabetes. Suggestions are also presented for overcoming some of these challenges. Dove 2021-03-16 /pmc/articles/PMC7981142/ /pubmed/33758531 http://dx.doi.org/10.2147/PGPM.S271582 Text en © 2021 Unnikrishnan et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Review
Unnikrishnan, Ranjit
Radha, Venkatesan
Mohan, Viswanathan
Challenges Involved in Incorporating Personalised Treatment Plan as Routine Care of Patients with Diabetes
title Challenges Involved in Incorporating Personalised Treatment Plan as Routine Care of Patients with Diabetes
title_full Challenges Involved in Incorporating Personalised Treatment Plan as Routine Care of Patients with Diabetes
title_fullStr Challenges Involved in Incorporating Personalised Treatment Plan as Routine Care of Patients with Diabetes
title_full_unstemmed Challenges Involved in Incorporating Personalised Treatment Plan as Routine Care of Patients with Diabetes
title_short Challenges Involved in Incorporating Personalised Treatment Plan as Routine Care of Patients with Diabetes
title_sort challenges involved in incorporating personalised treatment plan as routine care of patients with diabetes
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7981142/
https://www.ncbi.nlm.nih.gov/pubmed/33758531
http://dx.doi.org/10.2147/PGPM.S271582
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