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Irradiation-Induced Activated Microglia Affect Brain Metastatic Colonization of NSCLC Cells via miR-9/CDH1 Axis

BACKGROUND AND PURPOSE: Brain metastasis is among the leading causes of death in patients with non-small-cell lung cancer (NSCLC). Through yet unknown mechanisms, prophylactic cranial irradiation (PCI) can significantly decrease the incidence of brain metastases. Given that PCI probably exerts indir...

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Detalles Bibliográficos
Autores principales: Jin, Yu, Kang, Yalin, Peng, Xiaohong, Yang, Li, Li, Qianxia, Mei, Qi, Chen, Xinyi, Hu, Guangyuan, Tang, Yang, Yuan, Xianglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7981147/
https://www.ncbi.nlm.nih.gov/pubmed/33758511
http://dx.doi.org/10.2147/OTT.S301412