Furan Derivatives and Polyketides from the Fungus Irpex lacteus

ABSTRACT: Eight new furan derivatives, irpexins A‒H (1‒8), two new polyketides, irpexins I and J (9 and 10), together with nine known compounds were isolated from the fermentation of Irpex lacteus. The structures and absolute configurations were elucidated on the basis of extensive spectroscopic met...

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Detalles Bibliográficos
Autores principales: Wang, Meng, Li, Zheng-Hui, Isaka, Masahiko, Liu, Ji-Kai, Feng, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7981371/
https://www.ncbi.nlm.nih.gov/pubmed/33180316
http://dx.doi.org/10.1007/s13659-020-00282-w
Descripción
Sumario:ABSTRACT: Eight new furan derivatives, irpexins A‒H (1‒8), two new polyketides, irpexins I and J (9 and 10), together with nine known compounds were isolated from the fermentation of Irpex lacteus. The structures and absolute configurations were elucidated on the basis of extensive spectroscopic methods and Mosher ester reaction. All compounds shows no cytotoxicity to human MCF-7 and Hela cancer cell lines at the concentration of 10 μM. GRAPHIC ABSTRACT: [Image: see text] ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s13659-020-00282-w) contains supplementary material, which is available to authorized users.

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