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Significant elevation of free itraconazole concentration at onset of adverse effects: A case report

Free itraconazole and hydroxyitraconazole concentrations were markedly elevated despite almost no changes in total concentrations when itraconazole was discontinued due to adverse effects. Elevated free itraconazole concentration may have a causal relationship with the development of adverse effects...

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Detalles Bibliográficos
Autores principales: Tanaka, Ryota, Suzuki, Yosuke, Matsumoto, Hiroyuki, Yamasue, Mari, Umeki, Kenji, Hashinaga, Kazuhiko, Tatsuta, Ryosuke, Hiramatsu, Kazufumi, Kamei, Katsuhiko, Kadota, Jun‐ichi, Itoh, Hiroki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7981736/
https://www.ncbi.nlm.nih.gov/pubmed/33768808
http://dx.doi.org/10.1002/ccr3.3726