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Comparison of flexible, open with semi-rigid, closed annuloplasty-rings for mitral valve repair

BACKGROUND: Mitral regurgitation is a frequent valvular disease, with an increasing prevalence. We analysed the long-term outcomes of mitral valve repair procedures conducted over the last 10 years in our clinic using almost exclusively two different annuloplasty ring types. METHODS: A single-centre...

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Autores principales: Cetinkaya, Ayse, Waheed, Maryam, Bramlage, Karin, Liakopoulos, Oliver Johannes, Zeriouh, Mohamed, Hein, Stefan, Bramlage, Peter, Schönburg, Markus, Choi, Yeong-Hoon, Richter, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7981851/
https://www.ncbi.nlm.nih.gov/pubmed/33743744
http://dx.doi.org/10.1186/s13019-021-01405-1
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author Cetinkaya, Ayse
Waheed, Maryam
Bramlage, Karin
Liakopoulos, Oliver Johannes
Zeriouh, Mohamed
Hein, Stefan
Bramlage, Peter
Schönburg, Markus
Choi, Yeong-Hoon
Richter, Manfred
author_facet Cetinkaya, Ayse
Waheed, Maryam
Bramlage, Karin
Liakopoulos, Oliver Johannes
Zeriouh, Mohamed
Hein, Stefan
Bramlage, Peter
Schönburg, Markus
Choi, Yeong-Hoon
Richter, Manfred
author_sort Cetinkaya, Ayse
collection PubMed
description BACKGROUND: Mitral regurgitation is a frequent valvular disease, with an increasing prevalence. We analysed the long-term outcomes of mitral valve repair procedures conducted over the last 10 years in our clinic using almost exclusively two different annuloplasty ring types. METHODS: A single-centre, retrospective analysis of mitral valve surgeries conducted between January 2005 and December 2015 for patients undergoing first-line mitral valve repair with either open (Cosgrove) or closed (CE Physio / Physio II) annuloplasty (OA or CA, respectively) rings. RESULTS: In total, 1120 patient documentations were available of which 528 underwent OA and 592 patients CA. The median age of patients was 64.0 years and 41.1% were female. The majority of these patients underwent the procedure because of degenerative valve disease. Rates of successful repair were about 90%, 72 h procedural mortality was 0.6% and the rate of re-intervention was 0.6% within the first 30 days. Functional (mitral regurgitation, left ventricular ejection fraction, left ventricular end-diastolic and systolic diameter and New York Heart Association class) as well as hard outcomes were comparable. 77.7 and 74.4% of patients were alive at the 10-year follow-up in the OA and CA groups, respectively. Upon multivariable adjustment, the hazard ratio was 0.926 (95% CI: 0.642–1.3135; p = 0.681). CONCLUSIONS: The functional outcome and survival rates up to 10 years after mitral valve repair were comparable using open and closed annuloplasty rings. Whether this means these rings are interchangeable or a carefully selection of the best-for-the-patient devices will be subject of future investigations.
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spelling pubmed-79818512021-03-22 Comparison of flexible, open with semi-rigid, closed annuloplasty-rings for mitral valve repair Cetinkaya, Ayse Waheed, Maryam Bramlage, Karin Liakopoulos, Oliver Johannes Zeriouh, Mohamed Hein, Stefan Bramlage, Peter Schönburg, Markus Choi, Yeong-Hoon Richter, Manfred J Cardiothorac Surg Research Article BACKGROUND: Mitral regurgitation is a frequent valvular disease, with an increasing prevalence. We analysed the long-term outcomes of mitral valve repair procedures conducted over the last 10 years in our clinic using almost exclusively two different annuloplasty ring types. METHODS: A single-centre, retrospective analysis of mitral valve surgeries conducted between January 2005 and December 2015 for patients undergoing first-line mitral valve repair with either open (Cosgrove) or closed (CE Physio / Physio II) annuloplasty (OA or CA, respectively) rings. RESULTS: In total, 1120 patient documentations were available of which 528 underwent OA and 592 patients CA. The median age of patients was 64.0 years and 41.1% were female. The majority of these patients underwent the procedure because of degenerative valve disease. Rates of successful repair were about 90%, 72 h procedural mortality was 0.6% and the rate of re-intervention was 0.6% within the first 30 days. Functional (mitral regurgitation, left ventricular ejection fraction, left ventricular end-diastolic and systolic diameter and New York Heart Association class) as well as hard outcomes were comparable. 77.7 and 74.4% of patients were alive at the 10-year follow-up in the OA and CA groups, respectively. Upon multivariable adjustment, the hazard ratio was 0.926 (95% CI: 0.642–1.3135; p = 0.681). CONCLUSIONS: The functional outcome and survival rates up to 10 years after mitral valve repair were comparable using open and closed annuloplasty rings. Whether this means these rings are interchangeable or a carefully selection of the best-for-the-patient devices will be subject of future investigations. BioMed Central 2021-03-20 /pmc/articles/PMC7981851/ /pubmed/33743744 http://dx.doi.org/10.1186/s13019-021-01405-1 Text en © The Author(s) 2021 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Cetinkaya, Ayse
Waheed, Maryam
Bramlage, Karin
Liakopoulos, Oliver Johannes
Zeriouh, Mohamed
Hein, Stefan
Bramlage, Peter
Schönburg, Markus
Choi, Yeong-Hoon
Richter, Manfred
Comparison of flexible, open with semi-rigid, closed annuloplasty-rings for mitral valve repair
title Comparison of flexible, open with semi-rigid, closed annuloplasty-rings for mitral valve repair
title_full Comparison of flexible, open with semi-rigid, closed annuloplasty-rings for mitral valve repair
title_fullStr Comparison of flexible, open with semi-rigid, closed annuloplasty-rings for mitral valve repair
title_full_unstemmed Comparison of flexible, open with semi-rigid, closed annuloplasty-rings for mitral valve repair
title_short Comparison of flexible, open with semi-rigid, closed annuloplasty-rings for mitral valve repair
title_sort comparison of flexible, open with semi-rigid, closed annuloplasty-rings for mitral valve repair
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7981851/
https://www.ncbi.nlm.nih.gov/pubmed/33743744
http://dx.doi.org/10.1186/s13019-021-01405-1
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