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Epigenetic evidence of an Ac/Dc axis by VPA and SAHA
BACKGROUND: Valproic acid (VPA) is one of the most commonly used anti-epileptic drugs with pharmacological actions on GABA and blocking voltage-gated ion channels. VPA also inhibits histone deacetylase (HDAC) activity. Suberoylanilide hydroxamic acid is also a member of a larger class of compounds t...
Autores principales: | Lunke, Sebastian, Maxwell, Scott, Khurana, Ishant, K.N., Harikrishnan, Okabe, Jun, Al-Hasani, Keith, El-Osta, Assam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7981901/ https://www.ncbi.nlm.nih.gov/pubmed/33743782 http://dx.doi.org/10.1186/s13148-021-01050-4 |
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