SVExpress: identifying gene features altered recurrently in expression with nearby structural variant breakpoints

BACKGROUND: Combined whole-genome sequencing (WGS) and RNA sequencing of cancers offer the opportunity to identify genes with altered expression due to genomic rearrangements. Somatic structural variants (SVs), as identified by WGS, can involve altered gene cis-regulation, gene fusions, copy number...

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Detalles Bibliográficos
Autores principales: Zhang, Yiqun, Chen, Fengju, Creighton, Chad J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Software
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7981925/
https://www.ncbi.nlm.nih.gov/pubmed/33743584
http://dx.doi.org/10.1186/s12859-021-04072-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7981925/
https://www.ncbi.nlm.nih.gov/pubmed/33743584
http://dx.doi.org/10.1186/s12859-021-04072-0

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