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SVExpress: identifying gene features altered recurrently in expression with nearby structural variant breakpoints
BACKGROUND: Combined whole-genome sequencing (WGS) and RNA sequencing of cancers offer the opportunity to identify genes with altered expression due to genomic rearrangements. Somatic structural variants (SVs), as identified by WGS, can involve altered gene cis-regulation, gene fusions, copy number...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7981925/ https://www.ncbi.nlm.nih.gov/pubmed/33743584 http://dx.doi.org/10.1186/s12859-021-04072-0 |