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Pheochromocytoma-related cardiomyopathy presenting as acute myocardial infarction: A case report

INTRODUCTION: Pheochromocytoma (PHEO)-related cardiomyopathy is a rare condition in which release of a large amount of catecholamines leads to severe vasoconstriction, coronary vasospasm, myocardial ischemia, injury, and necrosis. Its clinical manifestations can be similar to those of acute coronary...

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Autores principales: Jiang, Xuandong, Zhang, Weimin, Fang, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7982151/
https://www.ncbi.nlm.nih.gov/pubmed/33725969
http://dx.doi.org/10.1097/MD.0000000000024984
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author Jiang, Xuandong
Zhang, Weimin
Fang, Qiang
author_facet Jiang, Xuandong
Zhang, Weimin
Fang, Qiang
author_sort Jiang, Xuandong
collection PubMed
description INTRODUCTION: Pheochromocytoma (PHEO)-related cardiomyopathy is a rare condition in which release of a large amount of catecholamines leads to severe vasoconstriction, coronary vasospasm, myocardial ischemia, injury, and necrosis. Its clinical manifestations can be similar to those of acute coronary syndrome. PATIENT CONCERNS: A 63-year-old woman was diagnosed with acute non-ST segment elevation myocardial infarction following chest pain for 8 hours. The results of coronary angiography were normal. The patient developed dyspnea, cough with frothy pink sputum, paroxysmal sweating, arrhythmia, and blood pressure fluctuation, and was transferred to the intensive care unit for monitoring and treatment. DIAGNOSIS: PHEO, catecholamine cardiomyopathy (CICMP) INTERVENTION: After monitoring the pulse index continuous cardiac output and treatment with α and β adrenergic receptor blockers for 18 days, laparoscopic resection of the left adrenal mass was performed. OUTCOMES: The patient's condition improved and she was discharged 31 days after admission. Outpatient follow-up examinations 1 month and 1 year later did not show recurrence. LESSONS: PHEO can cause CICMP, the manifestations of which are partly similar to those of takotsubo cardiomyopathy (TTC). Once the patient's condition stabilizes, surgery should be considered. Fluid management is necessary, and agents such as α and β adrenergic receptor blockers should be administered.
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spelling pubmed-79821512021-03-23 Pheochromocytoma-related cardiomyopathy presenting as acute myocardial infarction: A case report Jiang, Xuandong Zhang, Weimin Fang, Qiang Medicine (Baltimore) 3900 INTRODUCTION: Pheochromocytoma (PHEO)-related cardiomyopathy is a rare condition in which release of a large amount of catecholamines leads to severe vasoconstriction, coronary vasospasm, myocardial ischemia, injury, and necrosis. Its clinical manifestations can be similar to those of acute coronary syndrome. PATIENT CONCERNS: A 63-year-old woman was diagnosed with acute non-ST segment elevation myocardial infarction following chest pain for 8 hours. The results of coronary angiography were normal. The patient developed dyspnea, cough with frothy pink sputum, paroxysmal sweating, arrhythmia, and blood pressure fluctuation, and was transferred to the intensive care unit for monitoring and treatment. DIAGNOSIS: PHEO, catecholamine cardiomyopathy (CICMP) INTERVENTION: After monitoring the pulse index continuous cardiac output and treatment with α and β adrenergic receptor blockers for 18 days, laparoscopic resection of the left adrenal mass was performed. OUTCOMES: The patient's condition improved and she was discharged 31 days after admission. Outpatient follow-up examinations 1 month and 1 year later did not show recurrence. LESSONS: PHEO can cause CICMP, the manifestations of which are partly similar to those of takotsubo cardiomyopathy (TTC). Once the patient's condition stabilizes, surgery should be considered. Fluid management is necessary, and agents such as α and β adrenergic receptor blockers should be administered. Lippincott Williams & Wilkins 2021-03-19 /pmc/articles/PMC7982151/ /pubmed/33725969 http://dx.doi.org/10.1097/MD.0000000000024984 Text en Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by/4.0 This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0
spellingShingle 3900
Jiang, Xuandong
Zhang, Weimin
Fang, Qiang
Pheochromocytoma-related cardiomyopathy presenting as acute myocardial infarction: A case report
title Pheochromocytoma-related cardiomyopathy presenting as acute myocardial infarction: A case report
title_full Pheochromocytoma-related cardiomyopathy presenting as acute myocardial infarction: A case report
title_fullStr Pheochromocytoma-related cardiomyopathy presenting as acute myocardial infarction: A case report
title_full_unstemmed Pheochromocytoma-related cardiomyopathy presenting as acute myocardial infarction: A case report
title_short Pheochromocytoma-related cardiomyopathy presenting as acute myocardial infarction: A case report
title_sort pheochromocytoma-related cardiomyopathy presenting as acute myocardial infarction: a case report
topic 3900
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7982151/
https://www.ncbi.nlm.nih.gov/pubmed/33725969
http://dx.doi.org/10.1097/MD.0000000000024984
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