Endothelial dysfunction in COVID-19 calls for immediate attention: the emerging roles of the endothelium in inflammation caused by SARS-CoV-2

The COVID-19 pandemic has caused numerous deaths around the world. A growing body of evidence points to the important role of overwhelming inflammatory responses in the pathogenesis of COVID-19 and the effectiveness of anti-inflammation therapy against COVID-19 is emerging. In addition to affecting...

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Autores principales: Hang, Weijian, Chen, Chen, Zhang, Xin A., Wang, Dao Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2021
Materias:
Letter to Frontiers of Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7982315/
https://www.ncbi.nlm.nih.gov/pubmed/33748924
http://dx.doi.org/10.1007/s11684-021-0831-z
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author Hang, Weijian
Chen, Chen
Zhang, Xin A.
Wang, Dao Wen
author_facet Hang, Weijian
Chen, Chen
Zhang, Xin A.
Wang, Dao Wen
author_sort Hang, Weijian
collection PubMed
description The COVID-19 pandemic has caused numerous deaths around the world. A growing body of evidence points to the important role of overwhelming inflammatory responses in the pathogenesis of COVID-19 and the effectiveness of anti-inflammation therapy against COVID-19 is emerging. In addition to affecting the lungs, COVID-19 can be a severe systemic inflammatory disease that is related to endothelial dysfunction. We are calling for closer attention to endothelial dysfunction in COVID-19 not only for fully revealing the pathogenic mechanism of COVID-19 but also for properly adjusting the strategy of clinical intervention.
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spelling pubmed-79823152021-03-23 Endothelial dysfunction in COVID-19 calls for immediate attention: the emerging roles of the endothelium in inflammation caused by SARS-CoV-2 Hang, Weijian Chen, Chen Zhang, Xin A. Wang, Dao Wen Front Med Letter to Frontiers of Medicine The COVID-19 pandemic has caused numerous deaths around the world. A growing body of evidence points to the important role of overwhelming inflammatory responses in the pathogenesis of COVID-19 and the effectiveness of anti-inflammation therapy against COVID-19 is emerging. In addition to affecting the lungs, COVID-19 can be a severe systemic inflammatory disease that is related to endothelial dysfunction. We are calling for closer attention to endothelial dysfunction in COVID-19 not only for fully revealing the pathogenic mechanism of COVID-19 but also for properly adjusting the strategy of clinical intervention. Higher Education Press 2021-03-21 2021 /pmc/articles/PMC7982315/ /pubmed/33748924 http://dx.doi.org/10.1007/s11684-021-0831-z Text en © Higher Education Press 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Letter to Frontiers of Medicine
Hang, Weijian
Chen, Chen
Zhang, Xin A.
Wang, Dao Wen
Endothelial dysfunction in COVID-19 calls for immediate attention: the emerging roles of the endothelium in inflammation caused by SARS-CoV-2
title Endothelial dysfunction in COVID-19 calls for immediate attention: the emerging roles of the endothelium in inflammation caused by SARS-CoV-2
title_full Endothelial dysfunction in COVID-19 calls for immediate attention: the emerging roles of the endothelium in inflammation caused by SARS-CoV-2
title_fullStr Endothelial dysfunction in COVID-19 calls for immediate attention: the emerging roles of the endothelium in inflammation caused by SARS-CoV-2
title_full_unstemmed Endothelial dysfunction in COVID-19 calls for immediate attention: the emerging roles of the endothelium in inflammation caused by SARS-CoV-2
title_short Endothelial dysfunction in COVID-19 calls for immediate attention: the emerging roles of the endothelium in inflammation caused by SARS-CoV-2
title_sort endothelial dysfunction in covid-19 calls for immediate attention: the emerging roles of the endothelium in inflammation caused by sars-cov-2
topic Letter to Frontiers of Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7982315/
https://www.ncbi.nlm.nih.gov/pubmed/33748924
http://dx.doi.org/10.1007/s11684-021-0831-z
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