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Inhibition of TLR4/MAPKs Pathway Contributes to the Protection of Salvianolic Acid A Against Lipotoxicity-Induced Myocardial Damage in Cardiomyocytes and Obese Mice
The occurrence of lipotoxicity during obesity-associated cardiomyopathy is detrimental to health. Salvianolic acid A (SAA), a natural polyphenol extract of Salvia miltiorrhiza Bunge (Danshen in China), is known to be cardioprotective. However, its clinical benefits against obesity-associated cardiom...
Autores principales: | Yang, Zhen, Chen, Yanli, Yan, Zhaoyuan, Xu, Tian Tian, Wu, Xiangyao, Pi, Aiwen, Liu, Qingsheng, Chai, Hui, Li, Songtao, Dou, Xiaobing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7982403/ https://www.ncbi.nlm.nih.gov/pubmed/33762947 http://dx.doi.org/10.3389/fphar.2021.627123 |
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