Cargando…

Autophagy Mediates Leptin-Induced Migration and ERK Activation in Breast Cancer Cells

Autophagy is an intracellular recycling process active in eukaryotic cells that involves the formation of an autophagosome which delivers cytoplasmic components to the lysosome for degradation. This process occurs at low rates under basal conditions, but it can be induced by diverse types of stress...

Descripción completa

Detalles Bibliográficos
Autores principales:	García-Miranda, Alin, Solano-Alcalá, Karen Aylín, Montes-Alvarado, José Benito, Rosas-Cruz, Arely, Reyes-Leyva, Julio, Navarro-Tito, Napoleón, Maycotte, Paola, Castañeda-Saucedo, Eduardo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7982408/ https://www.ncbi.nlm.nih.gov/pubmed/33763424 http://dx.doi.org/10.3389/fcell.2021.644851

Ejemplares similares

Adipokines as Regulators of Autophagy in Obesity-Linked Cancer
por: García-Miranda, Alin, et al.
Publicado: (2022)

Autophagy Inhibition Induces the Secretion of Macrophage Migration Inhibitory Factor (MIF) with Autocrine and Paracrine Effects on the Promotion of Malignancy in Breast Cancer
por: Cotzomi-Ortega, Israel, et al.
Publicado: (2020)

Autophagy and Its Role in Protein Secretion: Implications for Cancer Therapy
por: Cotzomi-Ortega, Israel, et al.
Publicado: (2018)

Autophagy and Its Relationship to Epithelial to Mesenchymal Transition: When Autophagy Inhibition for Cancer Therapy Turns Counterproductive
por: Rojas-Sanchez, Guadalupe, et al.
Publicado: (2019)

Leptin induces cell migration and invasion in a FAK-Src-dependent manner in breast cancer cells
por: Juárez-Cruz, Juan Carlos, et al.
Publicado: (2019)

Signaling Pathways Induced by Leptin during Epithelial–Mesenchymal Transition in Breast Cancer
por: Olea-Flores, Monserrat, et al.
Publicado: (2018)

New Actors Driving the Epithelial–Mesenchymal Transition in Cancer: The Role of Leptin
por: Olea-Flores, Monserrat, et al.
Publicado: (2020)

Breast Cancer Subtypes Present a Differential Production of Reactive Oxygen Species (ROS) and Susceptibility to Antioxidant Treatment
por: Sarmiento-Salinas, Fabiola Lilí, et al.
Publicado: (2019)

Leptin suppresses development of GLP-1 inputs to the paraventricular nucleus of the hypothalamus
por: Biddinger, Jessica E, et al.
Publicado: (2020)

ERK1 and ERK2 Map Kinases: Specific Roles or Functional Redundancy?
por: Buscà, Roser, et al.
Publicado: (2016)

ERK5 Inhibition Induces Autophagy-Mediated Cancer Cell Death by Activating ER Stress
por: Gámez-García, Andrés, et al.
Publicado: (2021)

Hypothalamic ERK Mediates the Anorectic and Thermogenic Sympathetic Effects of Leptin
por: Rahmouni, Kamal, et al.
Publicado: (2009)

Spatial and Temporal Analysis of Active ERK in the C. elegans Germline
por: Gervaise, Amanda L., et al.
Publicado: (2016)

ERK5 Signalling and Resistance to ERK1/2 Pathway Therapeutics: The Path Less Travelled?
por: Cook, Simon J., et al.
Publicado: (2022)

Extracellular-Signal Regulated Kinase: A Central Molecule Driving Epithelial–Mesenchymal Transition in Cancer
por: Olea-Flores, Monserrat, et al.
Publicado: (2019)

Erk1/2 Mediates Leptin Receptor Signaling in the Ventral Tegmental Area
por: Trinko, Richard, et al.
Publicado: (2011)

Ezrin and E-cadherin expression profile in cervical cytology: a prognostic marker for tumor progression in cervical cancer
por: Zacapala-Gómez, Ana E., et al.
Publicado: (2018)

Retrograde ERK activation waves drive base-to-apex multicellular flow in murine cochlear duct morphogenesis
por: Ishii, Mamoru, et al.
Publicado: (2021)

Live-imaging of endothelial Erk activity reveals dynamic and sequential signalling events during regenerative angiogenesis
por: Okuda, Kazuhide S, et al.
Publicado: (2021)

Ficus crocata leaf extracts decrease the proliferation and invasiveness of breast cancer cells
por: Cayetano-Salazar, Lorena, et al.
Publicado: (2022)

RAB23 coordinates early osteogenesis by repressing FGF10-pERK1/2 and GLI1
por: Hasan, Md Rakibul, et al.
Publicado: (2020)

ERK5 and Cell Proliferation: Nuclear Localization Is What Matters
por: Gomez, Nestor, et al.
Publicado: (2016)

The significance of ERK5 catalytic-independent functions in disease pathways
por: Le, Nhat-Tu
Publicado: (2023)

An ERK5–KLF2 signalling module regulates early embryonic gene expression and telomere rejuvenation in stem cells
por: Brown, Helen A., et al.
Publicado: (2021)

Gain-of-Function Mutations in the Toll-Like Receptor Pathway: TPL2-Mediated ERK1/ERK2 MAPK Activation, a Path to Tumorigenesis in Lymphoid Neoplasms?
por: Rousseau, Simon, et al.
Publicado: (2016)

Playing the Whack-A-Mole Game: ERK5 Activation Emerges Among the Resistance Mechanisms to RAF-MEK1/2-ERK1/2- Targeted Therapy
por: Tubita, Alessandro, et al.
Publicado: (2021)

The role of the ERK signaling pathway in promoting angiogenesis for treating ischemic diseases
por: Song, Yue-Yue, et al.
Publicado: (2023)

Leptin and leptin receptor polymorphisms are associated with poor outcome (death) in patients with non-appendicular secondary peritonitis
por: Bracho-Riquelme, Rodolfo L, et al.
Publicado: (2011)

Editorial: Targeting redox regulation and autophagy systems for cancer therapy
por: Zhang, Junmin, et al.
Publicado: (2023)

Leptin Promotes Expression of EMT-Related Transcription Factors and Invasion in a Src and FAK-Dependent Pathway in MCF10A Mammary Epithelial Cells
por: Olea-Flores, Monserrat, et al.
Publicado: (2019)

Taurine Attenuates the Hypotaurine-Induced Progression of CRC via ERK/RSK Signaling
por: Hou, Xiaodan, et al.
Publicado: (2021)

Adipokine Leptin Co-operates With Mechanosensitive Ca(2 +)-Channels and Triggers Actomyosin-Mediated Motility of Breast Epithelial Cells
por: Acheva, Anna, et al.
Publicado: (2021)

Leptin Signaling in the Ovary of Diet-Induced Obese Mice Regulates Activation of NOD-Like Receptor Protein 3 Inflammasome
por: Adamowski, Marek, et al.
Publicado: (2021)

Leptin Inhibits Neutrophil Apoptosis in Children via ERK/NF-κB-Dependent Pathways
por: Sun, Zhizhi, et al.
Publicado: (2013)

Fast Dynamic in vivo Monitoring of Erk Activity at Single Cell Resolution in DREKA Zebrafish
por: Mayr, Vanessa, et al.
Publicado: (2018)

Racially Disparate Expression of mTOR/ERK-1/2 Allied Proteins in Cancer
por: Mishra, Sanjay, et al.
Publicado: (2021)

ERK3 and DGKζ interact to modulate cell motility in lung cancer cells
por: Myers, Amanda K., et al.
Publicado: (2023)

Leptin and TGF-β1 Downregulate PREP1 Expression in Human Adipose-Derived Mesenchymal Stem Cells and Mature Adipocytes
por: Bruno, Andreina, et al.
Publicado: (2021)

Glycogene expression profiles based on microarray data from cervical carcinoma HeLa cells with partially silenced E6 and E7 HPV oncogenes
por: Aco-Tlachi, Miguel, et al.
Publicado: (2018)

Wwox Deficiency Causes Downregulation of Prosurvival ERK Signaling and Abnormal Homeostatic Responses in Mouse Skin
por: Chou, Ying-Tsen, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_n75ds5273ssgrt4jc2f457dspq