Microfluidics in Sickle Cell Disease Research: State of the Art and a Perspective Beyond the Flow Problem

Sickle cell disease (SCD) is the monogenic hemoglobinopathy where mutated sickle hemoglobin molecules polymerize to form long fibers under deoxygenated state and deform red blood cells (RBCs) into predominantly sickle form. Sickled RBCs stick to the vascular bed and obstruct blood flow in extreme co...

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Detalles Bibliográficos
Autores principales: Aich, Anupam, Lamarre, Yann, Sacomani, Daniel Pereira, Kashima, Simone, Covas, Dimas Tadeu, de la Torre, Lucimara Gaziola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7982466/
https://www.ncbi.nlm.nih.gov/pubmed/33763448
http://dx.doi.org/10.3389/fmolb.2020.558982

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