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S-Allylmercaptocysteine improves alcoholic liver disease partly through a direct modulation of insulin receptor signaling

Alcoholic liver disease (ALD) causes insulin resistance, lipid metabolism dysfunction, and inflammation. We investigated the protective effects and direct regulating target of S-allylmercaptocysteine (SAMC) from aged garlic on liver cell injury. A chronic ethanol-fed ALD in vivo model (the NIAAA mod...

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Detalles Bibliográficos
Autores principales: Luo, Pingping, Zheng, Ming, Zhang, Rui, Zhang, Hong, Liu, Yingxia, Li, Wei, Sun, Xiaoming, Yu, Qian, Tipoe, George L., Xiao, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7982498/
https://www.ncbi.nlm.nih.gov/pubmed/33777674
http://dx.doi.org/10.1016/j.apsb.2020.11.006