Constitutive androstane receptor induced-hepatomegaly and liver regeneration is partially via yes-associated protein activation

The constitutive androstane receptor (CAR, NR3I1) belongs to nuclear receptor superfamily. It was reported that CAR agonist TCPOBOP induces hepatomegaly but the underlying mechanism remains largely unknown. Yes-associated protein (YAP) is a potent regulator of organ size. The aim of this study is to...

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Detalles Bibliográficos
Autores principales: Gao, Yue, Fan, Shicheng, Li, Hua, Jiang, Yiming, Yao, Xinpeng, Zhu, Shuguang, Yang, Xiao, Wang, Ruimin, Tian, Jianing, Gonzalez, Frank J., Huang, Min, Bi, Huichang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7982502/
https://www.ncbi.nlm.nih.gov/pubmed/33777678
http://dx.doi.org/10.1016/j.apsb.2020.11.021

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