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3D-FV-FE Aeroacoustic Larynx Model for Investigation of Functional Based Voice Disorders

For the clinical analysis of underlying mechanisms of voice disorders, we developed a numerical aeroacoustic larynx model, called simVoice, that mimics commonly observed functional laryngeal disorders as glottal insufficiency and vibrational left-right asymmetries. The model is a combination of the...

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Autores principales: Falk, Sebastian, Kniesburges, Stefan, Schoder, Stefan, Jakubaß, Bernhard, Maurerlehner, Paul, Echternach, Matthias, Kaltenbacher, Manfred, Döllinger, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7982522/
https://www.ncbi.nlm.nih.gov/pubmed/33762964
http://dx.doi.org/10.3389/fphys.2021.616985
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author Falk, Sebastian
Kniesburges, Stefan
Schoder, Stefan
Jakubaß, Bernhard
Maurerlehner, Paul
Echternach, Matthias
Kaltenbacher, Manfred
Döllinger, Michael
author_facet Falk, Sebastian
Kniesburges, Stefan
Schoder, Stefan
Jakubaß, Bernhard
Maurerlehner, Paul
Echternach, Matthias
Kaltenbacher, Manfred
Döllinger, Michael
author_sort Falk, Sebastian
collection PubMed
description For the clinical analysis of underlying mechanisms of voice disorders, we developed a numerical aeroacoustic larynx model, called simVoice, that mimics commonly observed functional laryngeal disorders as glottal insufficiency and vibrational left-right asymmetries. The model is a combination of the Finite Volume (FV) CFD solver Star-CCM+ and the Finite Element (FE) aeroacoustic solver CFS++. simVoice models turbulence using Large Eddy Simulations (LES) and the acoustic wave propagation with the perturbed convective wave equation (PCWE). Its geometry corresponds to a simplified larynx and a vocal tract model representing the vowel /a/. The oscillations of the vocal folds are externally driven. In total, 10 configurations with different degrees of functional-based disorders were simulated and analyzed. The energy transfer between the glottal airflow and the vocal folds decreases with an increasing glottal insufficiency and potentially reflects the higher effort during speech for patients being concerned. This loss of energy transfer may also have an essential influence on the quality of the sound signal as expressed by decreasing sound pressure level (SPL), Cepstral Peak Prominence (CPP), and Vocal Efficiency (VE). Asymmetry in the vocal fold oscillations also reduces the quality of the sound signal. However, simVoice confirmed previous clinical and experimental observations that a high level of glottal insufficiency worsens the acoustic signal quality more than oscillatory left-right asymmetry. Both symptoms in combination will further reduce the quality of the sound signal. In summary, simVoice allows for detailed analysis of the origins of disordered voice production and hence fosters the further understanding of laryngeal physiology, including occurring dependencies. A current walltime of 10 h/cycle is, with a prospective increase in computing power, auspicious for a future clinical use of simVoice.
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spelling pubmed-79825222021-03-23 3D-FV-FE Aeroacoustic Larynx Model for Investigation of Functional Based Voice Disorders Falk, Sebastian Kniesburges, Stefan Schoder, Stefan Jakubaß, Bernhard Maurerlehner, Paul Echternach, Matthias Kaltenbacher, Manfred Döllinger, Michael Front Physiol Physiology For the clinical analysis of underlying mechanisms of voice disorders, we developed a numerical aeroacoustic larynx model, called simVoice, that mimics commonly observed functional laryngeal disorders as glottal insufficiency and vibrational left-right asymmetries. The model is a combination of the Finite Volume (FV) CFD solver Star-CCM+ and the Finite Element (FE) aeroacoustic solver CFS++. simVoice models turbulence using Large Eddy Simulations (LES) and the acoustic wave propagation with the perturbed convective wave equation (PCWE). Its geometry corresponds to a simplified larynx and a vocal tract model representing the vowel /a/. The oscillations of the vocal folds are externally driven. In total, 10 configurations with different degrees of functional-based disorders were simulated and analyzed. The energy transfer between the glottal airflow and the vocal folds decreases with an increasing glottal insufficiency and potentially reflects the higher effort during speech for patients being concerned. This loss of energy transfer may also have an essential influence on the quality of the sound signal as expressed by decreasing sound pressure level (SPL), Cepstral Peak Prominence (CPP), and Vocal Efficiency (VE). Asymmetry in the vocal fold oscillations also reduces the quality of the sound signal. However, simVoice confirmed previous clinical and experimental observations that a high level of glottal insufficiency worsens the acoustic signal quality more than oscillatory left-right asymmetry. Both symptoms in combination will further reduce the quality of the sound signal. In summary, simVoice allows for detailed analysis of the origins of disordered voice production and hence fosters the further understanding of laryngeal physiology, including occurring dependencies. A current walltime of 10 h/cycle is, with a prospective increase in computing power, auspicious for a future clinical use of simVoice. Frontiers Media S.A. 2021-03-08 /pmc/articles/PMC7982522/ /pubmed/33762964 http://dx.doi.org/10.3389/fphys.2021.616985 Text en Copyright © 2021 Falk, Kniesburges, Schoder, Jakubaß, Maurerlehner, Echternach, Kaltenbacher and Döllinger. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Physiology
Falk, Sebastian
Kniesburges, Stefan
Schoder, Stefan
Jakubaß, Bernhard
Maurerlehner, Paul
Echternach, Matthias
Kaltenbacher, Manfred
Döllinger, Michael
3D-FV-FE Aeroacoustic Larynx Model for Investigation of Functional Based Voice Disorders
title 3D-FV-FE Aeroacoustic Larynx Model for Investigation of Functional Based Voice Disorders
title_full 3D-FV-FE Aeroacoustic Larynx Model for Investigation of Functional Based Voice Disorders
title_fullStr 3D-FV-FE Aeroacoustic Larynx Model for Investigation of Functional Based Voice Disorders
title_full_unstemmed 3D-FV-FE Aeroacoustic Larynx Model for Investigation of Functional Based Voice Disorders
title_short 3D-FV-FE Aeroacoustic Larynx Model for Investigation of Functional Based Voice Disorders
title_sort 3d-fv-fe aeroacoustic larynx model for investigation of functional based voice disorders
topic Physiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7982522/
https://www.ncbi.nlm.nih.gov/pubmed/33762964
http://dx.doi.org/10.3389/fphys.2021.616985
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