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Integration of comprehensive genomic profiling, tumor mutational burden, and PD‐L1 expression to identify novel biomarkers of immunotherapy in non‐small cell lung cancer
OBJECTIVES: This study aimed to explore the novel biomarkers for immune checkpoint inhibitor (ICI) responses in non‐small cell lung cancer (NSCLC) by integrating genomic profiling, tumor mutational burden (TMB), and expression of programmed death receptor 1 ligand (PD‐L1). MATERIALS AND METHODS: Tum...
Autores principales: | Shi, Yunfei, Lei, Youming, Liu, Li, Zhang, Shiyue, Wang, Wenjing, Zhao, Juan, Zhao, Songhui, Dong, Xiaowei, Yao, Ming, Wang, Kai, Zhou, Qing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7982619/ https://www.ncbi.nlm.nih.gov/pubmed/33655698 http://dx.doi.org/10.1002/cam4.3649 |
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