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XMD-17-51 Inhibits DCLK1 Kinase and Prevents Lung Cancer Progression
Doublecortin-like kinase 1 (DCLK1) is a cancer stem cell marker that is highly expressed in various types of human cancer, and a protein kinase target for cancer therapy that is attracting increasing interest. However, no drug candidates targeting DCLK1 kinase have been developed in clinical trials...
Autores principales: | Yang, Wei-Qiang, Zhao, Wei-Jun, Zhu, Liu-Lian, Xu, Shuai-Jun, Zhang, Xue-Lin, Liang, Yong, Ding, Xiao-Fei, Kiselyov, Alexander, Chen, Guang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7982674/ https://www.ncbi.nlm.nih.gov/pubmed/33762936 http://dx.doi.org/10.3389/fphar.2021.603453 |
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