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A Western diet impairs CNS energy homeostasis and recovery after spinal cord injury: Link to astrocyte metabolism
A diet high in fat and sucrose (HFHS), the so-called Western diet promotes metabolic syndrome, a significant comorbidity for individuals with spinal cord injury (SCI). Here we demonstrate that the spinal cord of mice consuming HFHS expresses reduced insulin-like growth factor 1 (IGF-1) and its recep...
Autores principales: | Kim, Ha Neui, Langley, Monica R., Simon, Whitney L., Yoon, Hyesook, Kleppe, Laurel, Lanza, Ian R., LeBrasseur, Nathan K., Matveyenko, Aleksey, Scarisbrick, Isobel A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7982964/ https://www.ncbi.nlm.nih.gov/pubmed/32376475 http://dx.doi.org/10.1016/j.nbd.2020.104934 |
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