Critical analysis of two cases of major crossmatch incompatibility in tertiary care hospital in Delhi

Rh blood group is one of the most complexes of the human blood groups system. RHD gene encodes the D antigen, and the RHCE encodes the C, c, E, and e antigens. Out of these, Rh D antigen is the most immunogenic while e antigen is the least immunogenic. Rh antibodies are produced in Rh-negative indiv...

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Autores principales: Puri, Vandana, Sharma, Geetika, Chhikara, Aruna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7983140/
https://www.ncbi.nlm.nih.gov/pubmed/33767549
http://dx.doi.org/10.4103/ajts.AJTS_155_17
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author Puri, Vandana
Sharma, Geetika
Chhikara, Aruna
author_facet Puri, Vandana
Sharma, Geetika
Chhikara, Aruna
author_sort Puri, Vandana
collection PubMed
description Rh blood group is one of the most complexes of the human blood groups system. RHD gene encodes the D antigen, and the RHCE encodes the C, c, E, and e antigens. Out of these, Rh D antigen is the most immunogenic while e antigen is the least immunogenic. Rh antibodies are produced in Rh-negative individuals following sensitization which occurs either through pregnancy or during blood transfusion. We hereby report two cases of anti-e antibody, both presenting as major crossmatch incompatibility.
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spelling pubmed-79831402021-03-24 Critical analysis of two cases of major crossmatch incompatibility in tertiary care hospital in Delhi Puri, Vandana Sharma, Geetika Chhikara, Aruna Asian J Transfus Sci Case Report Rh blood group is one of the most complexes of the human blood groups system. RHD gene encodes the D antigen, and the RHCE encodes the C, c, E, and e antigens. Out of these, Rh D antigen is the most immunogenic while e antigen is the least immunogenic. Rh antibodies are produced in Rh-negative individuals following sensitization which occurs either through pregnancy or during blood transfusion. We hereby report two cases of anti-e antibody, both presenting as major crossmatch incompatibility. Wolters Kluwer - Medknow 2020 2020-12-19 /pmc/articles/PMC7983140/ /pubmed/33767549 http://dx.doi.org/10.4103/ajts.AJTS_155_17 Text en Copyright: © 2020 Asian Journal of Transfusion Science http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Puri, Vandana
Sharma, Geetika
Chhikara, Aruna
Critical analysis of two cases of major crossmatch incompatibility in tertiary care hospital in Delhi
title Critical analysis of two cases of major crossmatch incompatibility in tertiary care hospital in Delhi
title_full Critical analysis of two cases of major crossmatch incompatibility in tertiary care hospital in Delhi
title_fullStr Critical analysis of two cases of major crossmatch incompatibility in tertiary care hospital in Delhi
title_full_unstemmed Critical analysis of two cases of major crossmatch incompatibility in tertiary care hospital in Delhi
title_short Critical analysis of two cases of major crossmatch incompatibility in tertiary care hospital in Delhi
title_sort critical analysis of two cases of major crossmatch incompatibility in tertiary care hospital in delhi
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7983140/
https://www.ncbi.nlm.nih.gov/pubmed/33767549
http://dx.doi.org/10.4103/ajts.AJTS_155_17
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