Prevention of acquired sensorineural hearing loss in mice by in vivo Htra2 gene editing

BACKGROUND: Aging, noise, infection, and ototoxic drugs are the major causes of human acquired sensorineural hearing loss, but treatment options are limited. CRISPR/Cas9 technology has tremendous potential to become a new therapeutic modality for acquired non-inherited sensorineural hearing loss. He...

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Detalles Bibliográficos
Autores principales: Gu, Xi, Wang, Daqi, Xu, Zhijiao, Wang, Jinghan, Guo, Luo, Chai, Renjie, Li, Genglin, Shu, Yilai, Li, Huawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7983387/
https://www.ncbi.nlm.nih.gov/pubmed/33752742
http://dx.doi.org/10.1186/s13059-021-02311-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7983387/
https://www.ncbi.nlm.nih.gov/pubmed/33752742
http://dx.doi.org/10.1186/s13059-021-02311-4

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