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Adaptive sample size determination for the development of clinical prediction models
BACKGROUND: We suggest an adaptive sample size calculation method for developing clinical prediction models, in which model performance is monitored sequentially as new data comes in. METHODS: We illustrate the approach using data for the diagnosis of ovarian cancer (n = 5914, 33% event fraction) an...
Autores principales: | Christodoulou, Evangelia, van Smeden, Maarten, Edlinger, Michael, Timmerman, Dirk, Wanitschek, Maria, Steyerberg, Ewout W., Van Calster, Ben |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7983402/ https://www.ncbi.nlm.nih.gov/pubmed/33745449 http://dx.doi.org/10.1186/s41512-021-00096-5 |
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