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Anterior Mediastinal Leiomyosarcoma: A Case Report and Literature Review
Primary mediastinal sarcomas are extremely rare. Additionally, mediastinal leiomyosarcomas account for approximately 9% of mediastinal sarcoma cases. Until date, only few cases of anterior mediastinal leiomyosarcomas have been reported. Herein, we report a case of an 85-year-old female with an anter...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7983580/ https://www.ncbi.nlm.nih.gov/pubmed/33776690 http://dx.doi.org/10.1159/000509772 |
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author | Ishikawa, Akira Kuraoka, Kazuya Zaitsu, Junichi Saito, Akihisa Kamigaichi, Atsushi Mimura, Takeshi Yamashita, Yoshinori Taniyama, Kiyomi |
author_facet | Ishikawa, Akira Kuraoka, Kazuya Zaitsu, Junichi Saito, Akihisa Kamigaichi, Atsushi Mimura, Takeshi Yamashita, Yoshinori Taniyama, Kiyomi |
author_sort | Ishikawa, Akira |
collection | PubMed |
description | Primary mediastinal sarcomas are extremely rare. Additionally, mediastinal leiomyosarcomas account for approximately 9% of mediastinal sarcoma cases. Until date, only few cases of anterior mediastinal leiomyosarcomas have been reported. Herein, we report a case of an 85-year-old female with an anterior mediastinal mass of 15 mm. Histological examination revealed spindle tumor cells showing a fascicular growth pattern. Immunohistochemically, the tumor cells were focal positive for desmin, calponin, and α-smooth muscle actin. The pathological diagnosis was leiomyosarcoma. In conclusion, we encountered a case of a very rare leiomyosarcoma that occurred in the anterior mediastinum, and our report may contribute to the understanding of this disease. |
format | Online Article Text |
id | pubmed-7983580 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | S. Karger AG |
record_format | MEDLINE/PubMed |
spelling | pubmed-79835802021-03-26 Anterior Mediastinal Leiomyosarcoma: A Case Report and Literature Review Ishikawa, Akira Kuraoka, Kazuya Zaitsu, Junichi Saito, Akihisa Kamigaichi, Atsushi Mimura, Takeshi Yamashita, Yoshinori Taniyama, Kiyomi Case Rep Oncol Case Report Primary mediastinal sarcomas are extremely rare. Additionally, mediastinal leiomyosarcomas account for approximately 9% of mediastinal sarcoma cases. Until date, only few cases of anterior mediastinal leiomyosarcomas have been reported. Herein, we report a case of an 85-year-old female with an anterior mediastinal mass of 15 mm. Histological examination revealed spindle tumor cells showing a fascicular growth pattern. Immunohistochemically, the tumor cells were focal positive for desmin, calponin, and α-smooth muscle actin. The pathological diagnosis was leiomyosarcoma. In conclusion, we encountered a case of a very rare leiomyosarcoma that occurred in the anterior mediastinum, and our report may contribute to the understanding of this disease. S. Karger AG 2021-02-25 /pmc/articles/PMC7983580/ /pubmed/33776690 http://dx.doi.org/10.1159/000509772 Text en Copyright © 2021 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission. |
spellingShingle | Case Report Ishikawa, Akira Kuraoka, Kazuya Zaitsu, Junichi Saito, Akihisa Kamigaichi, Atsushi Mimura, Takeshi Yamashita, Yoshinori Taniyama, Kiyomi Anterior Mediastinal Leiomyosarcoma: A Case Report and Literature Review |
title | Anterior Mediastinal Leiomyosarcoma: A Case Report and Literature Review |
title_full | Anterior Mediastinal Leiomyosarcoma: A Case Report and Literature Review |
title_fullStr | Anterior Mediastinal Leiomyosarcoma: A Case Report and Literature Review |
title_full_unstemmed | Anterior Mediastinal Leiomyosarcoma: A Case Report and Literature Review |
title_short | Anterior Mediastinal Leiomyosarcoma: A Case Report and Literature Review |
title_sort | anterior mediastinal leiomyosarcoma: a case report and literature review |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7983580/ https://www.ncbi.nlm.nih.gov/pubmed/33776690 http://dx.doi.org/10.1159/000509772 |
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