Essential genes in thyroid cancers: focus on fascin

Although thyroid cancers are not among common malignancies, they rank as the first prevalent endocrine cancers in human. According to the results of published studies it has been shown the gradual progress from normal to the neoplastic cell in the process of tumor formation is the result of sequenti...

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Autores principales: Samimi, Hilda, Zaki dizaji, Majid, Ghadami, Mohsen, Shahzadeh fazeli, Abolhasan, Khashayar, Patricia, Soleimani, Masoud, Larijani, Bagher, Haghpanah, Vahid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7983713/
https://www.ncbi.nlm.nih.gov/pubmed/23815863
http://dx.doi.org/10.1186/2251-6581-12-32
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author Samimi, Hilda
Zaki dizaji, Majid
Ghadami, Mohsen
Shahzadeh fazeli, Abolhasan
Khashayar, Patricia
Soleimani, Masoud
Larijani, Bagher
Haghpanah, Vahid
author_facet Samimi, Hilda
Zaki dizaji, Majid
Ghadami, Mohsen
Shahzadeh fazeli, Abolhasan
Khashayar, Patricia
Soleimani, Masoud
Larijani, Bagher
Haghpanah, Vahid
author_sort Samimi, Hilda
collection PubMed
description Although thyroid cancers are not among common malignancies, they rank as the first prevalent endocrine cancers in human. According to the results of published studies it has been shown the gradual progress from normal to the neoplastic cell in the process of tumor formation is the result of sequential genetic events. Among them we may point the mutations and rearrangements occurred in a group of proto-oncogenes, transcription factors and metastasis elements such as P53, RAS,RET,BRAF, PPARγ and Fascin. In the present article,we reviewed the most important essential genes in thyroid cancers, the role of epithelial mesenchymal transition and Fascin has been highlighted in this paper.
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spelling pubmed-79837132021-04-12 Essential genes in thyroid cancers: focus on fascin Samimi, Hilda Zaki dizaji, Majid Ghadami, Mohsen Shahzadeh fazeli, Abolhasan Khashayar, Patricia Soleimani, Masoud Larijani, Bagher Haghpanah, Vahid J Diabetes Metab Disord Review Article Although thyroid cancers are not among common malignancies, they rank as the first prevalent endocrine cancers in human. According to the results of published studies it has been shown the gradual progress from normal to the neoplastic cell in the process of tumor formation is the result of sequential genetic events. Among them we may point the mutations and rearrangements occurred in a group of proto-oncogenes, transcription factors and metastasis elements such as P53, RAS,RET,BRAF, PPARγ and Fascin. In the present article,we reviewed the most important essential genes in thyroid cancers, the role of epithelial mesenchymal transition and Fascin has been highlighted in this paper. BioMed Central 2013-07-01 /pmc/articles/PMC7983713/ /pubmed/23815863 http://dx.doi.org/10.1186/2251-6581-12-32 Text en © Samimi et al.; licensee BioMed Central Ltd. 2013 http://creativecommons.org/licenses/by/2.0 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Samimi, Hilda
Zaki dizaji, Majid
Ghadami, Mohsen
Shahzadeh fazeli, Abolhasan
Khashayar, Patricia
Soleimani, Masoud
Larijani, Bagher
Haghpanah, Vahid
Essential genes in thyroid cancers: focus on fascin
title Essential genes in thyroid cancers: focus on fascin
title_full Essential genes in thyroid cancers: focus on fascin
title_fullStr Essential genes in thyroid cancers: focus on fascin
title_full_unstemmed Essential genes in thyroid cancers: focus on fascin
title_short Essential genes in thyroid cancers: focus on fascin
title_sort essential genes in thyroid cancers: focus on fascin
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7983713/
https://www.ncbi.nlm.nih.gov/pubmed/23815863
http://dx.doi.org/10.1186/2251-6581-12-32
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