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Hypothesis: Tau pathology is an initiating factor in sporadic Alzheimer's disease

The etiology of the common, sporadic form of Alzheimer's disease (sAD) is unknown. We hypothesize that tau pathology within select projection neurons with susceptible microenvironments can initiate sAD. This postulate rests on extensive data demonstrating that in human brains tau pathology appe...

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Detalles Bibliográficos
Autores principales:	Arnsten, Amy F. T., Datta, Dibyadeep, Tredici, Kelly Del, Braak, Heiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Theoretical Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7983919/ https://www.ncbi.nlm.nih.gov/pubmed/33075193 http://dx.doi.org/10.1002/alz.12192

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