Reduced concentrations of the B cell cytokine interleukin 38 are associated with cardiovascular disease risk in overweight subjects

The IL‐1 family member IL‐38 (IL1F10) suppresses inflammatory and autoimmune conditions. Here, we report that plasma concentrations of IL‐38 in 288 healthy Europeans correlate positively with circulating memory B cells and plasmablasts. IL‐38 correlated negatively with age (p = 0.02) and was stable...

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Detalles Bibliográficos
Autores principales: de Graaf, Dennis M., Jaeger, Martin, van den Munckhof, Inge C. L., ter Horst, Rob, Schraa, Kiki, Zwaag, Jelle, Kox, Matthijs, Fujita, Mayumi, Yamauchi, Takeshi, Mercurio, Laura, Madonna, Stefania, Rutten, Joost H.W., de Graaf, Jacqueline, Riksen, Niels P., van de Veerdonk, Frank L., Netea, Mihai G., Joosten, Leo A.B., Dinarello, Charles A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Allergy and inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7983920/
https://www.ncbi.nlm.nih.gov/pubmed/33125159
http://dx.doi.org/10.1002/eji.201948390

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