Cargando…

ADP-Ribosylation Regulates the Signaling Function of IFN-γ

Murine T cells express the GPI-anchored ADP-ribosyltransferase 2.2 (ARTC2.2) on the cell surface. In response to T cell activation or extracellular NAD(+) or ATP-mediated gating of the P2X7 ion channel ARTC2.2 is shed from the cell surface as a soluble enzyme. Shedding alters the target specificity...

Descripción completa

Detalles Bibliográficos
Autores principales:	Menzel, Stephan, Koudelka, Tomas, Rissiek, Björn, Haag, Friedrich, Meyer-Schwesinger, Catherine, Tholey, Andreas, Koch-Nolte, Friedrich
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7983947/ https://www.ncbi.nlm.nih.gov/pubmed/33763084 http://dx.doi.org/10.3389/fimmu.2021.642545

Ejemplares similares

Identification of the Mouse T Cell ADP-Ribosylome Uncovers ARTC2.2 Mediated Regulation of CD73 by ADP-Ribosylation
por: Leutert, Mario, et al.
Publicado: (2021)

Tuning IL-2 signaling by ADP-ribosylation of CD25
por: Teege, Sophie, et al.
Publicado: (2015)

ADP-ribosylation of arginine
por: Laing, Sabrina, et al.
Publicado: (2010)

Ecto-ADP-ribosyltransferase ARTC2.1 functionally modulates FcγR1 and FcγR2B on murine microglia
por: Rissiek, Björn, et al.
Publicado: (2017)

In silico characterization of the family of PARP-like poly(ADP-ribosyl)transferases (pARTs)
por: Otto, Helge, et al.
Publicado: (2005)

P2X7 on Mouse T Cells: One Channel, Many Functions
por: Rissiek, Björn, et al.
Publicado: (2015)

Alternative Splicing of the N-Terminal Cytosolic and Transmembrane Domains of P2X7 Controls Gating of the Ion Channel by ADP-Ribosylation
por: Schwarz, Nicole, et al.
Publicado: (2012)

Nuclear ADP-ribosylation drives IFNγ-dependent STAT1α enhancer formation in macrophages
por: Gupte, Rebecca, et al.
Publicado: (2021)

Nanobody-Based Biologics for Modulating Purinergic Signaling in Inflammation and Immunity
por: Menzel, Stephan, et al.
Publicado: (2018)

In Vivo Blockade of Murine ARTC2.2 During Cell Preparation Preserves the Vitality and Function of Liver Tissue-Resident Memory T Cells
por: Rissiek, Björn, et al.
Publicado: (2018)

Serine ADP-ribosylation in Drosophila provides insights into the evolution of reversible ADP-ribosylation signalling
por: Fontana, Pietro, et al.
Publicado: (2023)

A cDNA Immunization Strategy to Generate Nanobodies against Membrane Proteins in Native Conformation
por: Eden, Thomas, et al.
Publicado: (2018)

Reversing ADP-ribosylation
por: Moeller, Giuliana Katharina, et al.
Publicado: (2017)

Evaluation of nanobody-based biologics targeting purinergic checkpoints in tumor models in vivo
por: Demeules, Mélanie, et al.
Publicado: (2022)

ADP-ribosylation signalling and human disease
por: Palazzo, Luca, et al.
Publicado: (2019)

Arginine-Specific Mono ADP-Ribosylation In Vitro of Antimicrobial Peptides by ADP-Ribosylating Toxins
por: Castagnini, Marta, et al.
Publicado: (2012)

Generation and Function of Non-cell-bound CD73 in Inflammation
por: Schneider, Enja, et al.
Publicado: (2019)

Reversible ADP-ribosylation of RNA
por: Munnur, Deeksha, et al.
Publicado: (2019)

The ADP-Ribosylating Toxins of Salmonella
por: Cheng, Rachel A., et al.
Publicado: (2019)

ADP-ribosylation of DNA and RNA()
por: Groslambert, Joséphine, et al.
Publicado: (2021)

Mouse CD38-Specific Heavy Chain Antibodies Inhibit CD38 GDPR-Cyclase Activity and Mediate Cytotoxicity Against Tumor Cells
por: Baum, Natalie, et al.
Publicado: (2021)

ADP-ribosyl-N(3): A Versatile Precursor for Divergent Syntheses of ADP-ribosylated Compounds
por: Li, Lingjun, et al.
Publicado: (2017)

Nanobodies as modulators of inflammation: potential applications for acute brain injury
por: Rissiek, Björn, et al.
Publicado: (2014)

Improved Functionality of Exhausted Intrahepatic CXCR5+ CD8+ T Cells Contributes to Chronic Antigen Clearance Upon Immunomodulation
por: Kumashie, Kingsley Gideon, et al.
Publicado: (2021)

Astrocytes and Microglia Are Resistant to NAD(+)-Mediated Cell Death Along the ARTC2/P2X7 Axis
por: Rissiek, Björn, et al.
Publicado: (2020)

Intracellular Mono-ADP-Ribosylation in Signaling and Disease
por: Bütepage, Mareike, et al.
Publicado: (2015)

CD38-Specific Biparatopic Heavy Chain Antibodies Display Potent Complement-Dependent Cytotoxicity Against Multiple Myeloma Cells
por: Schütze, Kerstin, et al.
Publicado: (2018)

ADP-ribosylation of actin by clostridial toxins
Publicado: (1989)

ADP-Ribosylation: Activation, Recognition, and Removal
por: Li, Nan, et al.
Publicado: (2014)

The Promise of Proteomics for the Study of ADP-Ribosylation
por: Daniels, Casey M., et al.
Publicado: (2015)

Wnt pathway activation by ADP-ribosylation
por: Yang, Eungi, et al.
Publicado: (2016)

The coronavirus nucleocapsid protein is ADP-ribosylated
por: Grunewald, Matthew E., et al.
Publicado: (2018)

Computational and Experimental Studies of ADP-Ribosylation
por: Hammond, Robert G., et al.
Publicado: (2017)

PARPs and ADP-ribosylation: 60 years on
por: Kraus, W. Lee
Publicado: (2020)

Targeting ADP-ribosylation as an antimicrobial strategy
por: Catara, Giuliana, et al.
Publicado: (2019)

Poly(ADP-Ribosyl) Code Functions
por: Maluchenko, N. V., et al.
Publicado: (2021)

ADP-ribosylation systems in bacteria and viruses
por: Mikolčević, Petra, et al.
Publicado: (2021)

ADP-Ribosylation and Antiviral Resistance in Plants
por: Spechenkova, Nadezhda, et al.
Publicado: (2023)

Origin, distribution, and function of three frequent coding polymorphisms in the gene for the human P2X7 ion channel
por: Schäfer, Waldemar, et al.
Publicado: (2022)

Regulation of Bone Morphogenetic Protein Signaling by ADP-ribosylation
por: Watanabe, Yukihide, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_e97d6b5ijhe9sj4f40u5rmvqa8