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Corneal and lens densitometry in patients with vernal keratoconjunctivitis
AIM: To evaluate corneal and crystalline lens densitometry in patients with vernal keratoconjunctivitis (VKC). METHODS: This is a case–control study. Patients with VKC and age–gender-matched healthy controls underwent a complete ophthalmologic examination with corneal and crystalline lens densitomet...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7983973/ https://www.ncbi.nlm.nih.gov/pubmed/33754236 http://dx.doi.org/10.1007/s10792-021-01822-0 |
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author | Yılmaz, Yusuf Cem Ipek, Sefik Can Ozer, Muhammet Derda |
author_facet | Yılmaz, Yusuf Cem Ipek, Sefik Can Ozer, Muhammet Derda |
author_sort | Yılmaz, Yusuf Cem |
collection | PubMed |
description | AIM: To evaluate corneal and crystalline lens densitometry in patients with vernal keratoconjunctivitis (VKC). METHODS: This is a case–control study. Patients with VKC and age–gender-matched healthy controls underwent a complete ophthalmologic examination with corneal and crystalline lens densitometry measurements. Additionally, the anterior chamber parameters comprise anterior and posterior K(mean) and astigmatism, anterior chamber depth (ACD), anterior chamber volume (ACV), anterior chamber angle (ACA), pachymeter, and corneal volume (CV). Patients who had clinically grade 0 or grade 1 VKC and with only tarsal conjunctiva involvement during the conductance of the study were included. The variables were compared statistically. RESULTS: One hundred and nine eyes were included in the study, in which fifty-one were in the VKC group. There were 25 males in the VKC group (26 female) and 22 males in the control group (36 female). A statistically significant difference was found between the groups in terms of posterior corneal astigmatism (p = 0.02). The mean corneal pachymeter, CV, ACD, ACA, and ACV were similar in both groups (p = 0.63, p = 0.26, p = 0.60, p = 0.41, and p = 0.32, respectively). The total mean corneal densitometry in the zones extending from 6 to 10 mm and 10 to 12 mm was increased in the VKC group compared to the control group (p = 0.04 and p = 0.012, respectively). The mean crystalline lens was found to be denser in the VKC group compared to the control group (8.96 ± 1.6 vs. 8.5 ± 0.57, respectively, p = 0.04). CONCLUSION: Posterior corneal astigmatism is increased in VKC cases in comparison with age- and gender-matched controls. The peripheral anterior 6–12 mm annular corneal zone showed increased corneal densitometry in VKC cases compared to the healthy subjects. Additionally, the lens clarity is found to be decreased subclinically in VKC cases compared to control cases. |
format | Online Article Text |
id | pubmed-7983973 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Springer Netherlands |
record_format | MEDLINE/PubMed |
spelling | pubmed-79839732021-03-23 Corneal and lens densitometry in patients with vernal keratoconjunctivitis Yılmaz, Yusuf Cem Ipek, Sefik Can Ozer, Muhammet Derda Int Ophthalmol Original Paper AIM: To evaluate corneal and crystalline lens densitometry in patients with vernal keratoconjunctivitis (VKC). METHODS: This is a case–control study. Patients with VKC and age–gender-matched healthy controls underwent a complete ophthalmologic examination with corneal and crystalline lens densitometry measurements. Additionally, the anterior chamber parameters comprise anterior and posterior K(mean) and astigmatism, anterior chamber depth (ACD), anterior chamber volume (ACV), anterior chamber angle (ACA), pachymeter, and corneal volume (CV). Patients who had clinically grade 0 or grade 1 VKC and with only tarsal conjunctiva involvement during the conductance of the study were included. The variables were compared statistically. RESULTS: One hundred and nine eyes were included in the study, in which fifty-one were in the VKC group. There were 25 males in the VKC group (26 female) and 22 males in the control group (36 female). A statistically significant difference was found between the groups in terms of posterior corneal astigmatism (p = 0.02). The mean corneal pachymeter, CV, ACD, ACA, and ACV were similar in both groups (p = 0.63, p = 0.26, p = 0.60, p = 0.41, and p = 0.32, respectively). The total mean corneal densitometry in the zones extending from 6 to 10 mm and 10 to 12 mm was increased in the VKC group compared to the control group (p = 0.04 and p = 0.012, respectively). The mean crystalline lens was found to be denser in the VKC group compared to the control group (8.96 ± 1.6 vs. 8.5 ± 0.57, respectively, p = 0.04). CONCLUSION: Posterior corneal astigmatism is increased in VKC cases in comparison with age- and gender-matched controls. The peripheral anterior 6–12 mm annular corneal zone showed increased corneal densitometry in VKC cases compared to the healthy subjects. Additionally, the lens clarity is found to be decreased subclinically in VKC cases compared to control cases. Springer Netherlands 2021-03-22 2021 /pmc/articles/PMC7983973/ /pubmed/33754236 http://dx.doi.org/10.1007/s10792-021-01822-0 Text en © The Author(s), under exclusive licence to Springer Nature B.V. 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Original Paper Yılmaz, Yusuf Cem Ipek, Sefik Can Ozer, Muhammet Derda Corneal and lens densitometry in patients with vernal keratoconjunctivitis |
title | Corneal and lens densitometry in patients with vernal keratoconjunctivitis |
title_full | Corneal and lens densitometry in patients with vernal keratoconjunctivitis |
title_fullStr | Corneal and lens densitometry in patients with vernal keratoconjunctivitis |
title_full_unstemmed | Corneal and lens densitometry in patients with vernal keratoconjunctivitis |
title_short | Corneal and lens densitometry in patients with vernal keratoconjunctivitis |
title_sort | corneal and lens densitometry in patients with vernal keratoconjunctivitis |
topic | Original Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7983973/ https://www.ncbi.nlm.nih.gov/pubmed/33754236 http://dx.doi.org/10.1007/s10792-021-01822-0 |
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