Drug‐drug interaction of atazanavir on UGT1A1‐mediated glucuronidation of molidustat in human

Molidustat is an oral inhibitor of hypoxia‐inducible factor (HIF) prolyl‐hydroxylase enhancing the erythropoietin (EPO) response to HIF; it is in clinical development for the treatment of anaemia related to chronic kidney disease. The predominant role of glucuronidation for molidustat clearance (for...

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Detalles Bibliográficos
Autores principales: van der Mey, Dorina, Gerisch, Michael, Jungmann, Natalia A., Kaiser, Andreas, Yoshikawa, Kenichi, Schulz, Simone, Radtke, Martin, Lentini, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
ORIGINAL ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7983974/
https://www.ncbi.nlm.nih.gov/pubmed/33232579
http://dx.doi.org/10.1111/bcpt.13538

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7983974/
https://www.ncbi.nlm.nih.gov/pubmed/33232579
http://dx.doi.org/10.1111/bcpt.13538

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