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Pharmacokinetic variability of factor VIII concentrates in Chinese pediatric patients with moderate or severe hemophilia A

IMPORTANCE: The use of factor VIII (FVIII) concentrates under pharmacokinetic (PK) guidance has become the main approach for treatment of hemophilia. However, limited PK research has been conducted in Chinese pediatric patients. OBJECTIVE: To investigate the PK parameters of various FVIII concentrat...

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Detalles Bibliográficos
Autores principales: Chen, Zhenping, Huang, Kun, Li, Gang, Zhen, Yingzi, Wu, Xinyi, Di, Ai, Liu, Guoqing, Li, Zekun, Alfonso, Iorio, Wu, Runhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7983998/
https://www.ncbi.nlm.nih.gov/pubmed/33778426
http://dx.doi.org/10.1002/ped4.12252

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