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Disease characteristics and neuropathological changes associated with cognitive dysfunction in obstructive sleep apnea
Obstructive sleep apnea (OSA) is a common sleep‐disordered breathing disease that often leads to many comorbidities (e.g., cognitive dysfunction), which adversely affect the quality of life for patients with OSA. Thus far, the underlying mechanisms of this dysfunction remain unclear. Many studies ha...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7984002/ https://www.ncbi.nlm.nih.gov/pubmed/33778428 http://dx.doi.org/10.1002/ped4.12247 |
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author | Ji, Tingting Li, Xiaodan Qiu, Yue Mei, Lin Jia, Xinbei Tai, Jun Guo, Yongli Zhang, Jie Wang, Shengcai Ni, Xin |
author_facet | Ji, Tingting Li, Xiaodan Qiu, Yue Mei, Lin Jia, Xinbei Tai, Jun Guo, Yongli Zhang, Jie Wang, Shengcai Ni, Xin |
author_sort | Ji, Tingting |
collection | PubMed |
description | Obstructive sleep apnea (OSA) is a common sleep‐disordered breathing disease that often leads to many comorbidities (e.g., cognitive dysfunction), which adversely affect the quality of life for patients with OSA. Thus far, the underlying mechanisms of this dysfunction remain unclear. Many studies have focused on OSA‐related characteristics, including intermittent hypoxemia and sleep fragmentation. There is increasing emphasis on neuroimaging studies to explore underlying relationships between neuropathological changes and cognitive dysfunction. This article reviews recent research progress concerning cognitive dysfunction associated with OSA to reveal potential mechanisms that contribute to this dysfunction. |
format | Online Article Text |
id | pubmed-7984002 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-79840022021-03-25 Disease characteristics and neuropathological changes associated with cognitive dysfunction in obstructive sleep apnea Ji, Tingting Li, Xiaodan Qiu, Yue Mei, Lin Jia, Xinbei Tai, Jun Guo, Yongli Zhang, Jie Wang, Shengcai Ni, Xin Pediatr Investig Review Obstructive sleep apnea (OSA) is a common sleep‐disordered breathing disease that often leads to many comorbidities (e.g., cognitive dysfunction), which adversely affect the quality of life for patients with OSA. Thus far, the underlying mechanisms of this dysfunction remain unclear. Many studies have focused on OSA‐related characteristics, including intermittent hypoxemia and sleep fragmentation. There is increasing emphasis on neuroimaging studies to explore underlying relationships between neuropathological changes and cognitive dysfunction. This article reviews recent research progress concerning cognitive dysfunction associated with OSA to reveal potential mechanisms that contribute to this dysfunction. John Wiley and Sons Inc. 2021-03-22 /pmc/articles/PMC7984002/ /pubmed/33778428 http://dx.doi.org/10.1002/ped4.12247 Text en © 2021 Chinese Medical Association. Pediatric Investigation published by John Wiley & Sons Australia, Ltd on behalf of Futang Research Center of Pediatric Development. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Review Ji, Tingting Li, Xiaodan Qiu, Yue Mei, Lin Jia, Xinbei Tai, Jun Guo, Yongli Zhang, Jie Wang, Shengcai Ni, Xin Disease characteristics and neuropathological changes associated with cognitive dysfunction in obstructive sleep apnea |
title | Disease characteristics and neuropathological changes associated with cognitive dysfunction in obstructive sleep apnea |
title_full | Disease characteristics and neuropathological changes associated with cognitive dysfunction in obstructive sleep apnea |
title_fullStr | Disease characteristics and neuropathological changes associated with cognitive dysfunction in obstructive sleep apnea |
title_full_unstemmed | Disease characteristics and neuropathological changes associated with cognitive dysfunction in obstructive sleep apnea |
title_short | Disease characteristics and neuropathological changes associated with cognitive dysfunction in obstructive sleep apnea |
title_sort | disease characteristics and neuropathological changes associated with cognitive dysfunction in obstructive sleep apnea |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7984002/ https://www.ncbi.nlm.nih.gov/pubmed/33778428 http://dx.doi.org/10.1002/ped4.12247 |
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