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Appended Aromatic Moieties in Flexible Bis‐3‐chloropiperidines Confer Tropism against Pancreatic Cancer Cells

Nitrogen mustards (NMs) are an old but still largely diffused class of anticancer drugs. However, spreading mechanisms of resistance undermine their efficacy and therapeutic applicability. To expand their antitumour value, we developed bis‐3‐chloropiperidines (B‐CePs), a new class of mustard‐based a...

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Detalles Bibliográficos
Autores principales: Carraro, Caterina, Helbing, Tim, Francke, Alexander, Zuravka, Ivonne, Sosic, Alice, De Franco, Michele, Gandin, Valentina, Gatto, Barbara, Göttlich, D. Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7984046/
https://www.ncbi.nlm.nih.gov/pubmed/33200541
http://dx.doi.org/10.1002/cmdc.202000814

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