APOE and dementia – resequencing and genotyping in 105,597 individuals

INTRODUCTION: The mechanism behind the strong association between the ɛ2/ɛ3/ɛ4 apolipoprotein E gene (APOE) polymorphism and Alzheimer's disease is not well‐characterized. Because low plasma levels of apoE associate with risk of dementia, genetic variants altering apoE levels in general may als...

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Detalles Bibliográficos
Autores principales: Rasmussen, Katrine L., Tybjærg‐Hansen, Anne, Nordestgaard, Børge G., Frikke‐Schmidt, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7984319/
https://www.ncbi.nlm.nih.gov/pubmed/32808727
http://dx.doi.org/10.1002/alz.12165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7984319/
https://www.ncbi.nlm.nih.gov/pubmed/32808727
http://dx.doi.org/10.1002/alz.12165

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