Genetic dissection of a major haplotype associated with arthritis reveal FcγR2b and FcγR3 to act additively

A haplotype with tightly linked Fc gamma receptor (FcγR) genes is known as a major locus controlling immune responses and autoimmune diseases, including arthritis. Here, we split a congenic fragment derived from the NOD mouse (Cia9) to study its effect on immune response and arthritis in mice. We fo...

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Detalles Bibliográficos
Autores principales: Vaartjes, Daniëlle, Klaczkowska, Dorota, Cragg, Mark S, Nandakumar, Kutty Selva, Bäckdahl, Liselotte, Holmdahl, Rikard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Immunodeficiencies and autoimmunity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7984332/
https://www.ncbi.nlm.nih.gov/pubmed/33244759
http://dx.doi.org/10.1002/eji.202048605

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7984332/
https://www.ncbi.nlm.nih.gov/pubmed/33244759
http://dx.doi.org/10.1002/eji.202048605

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