Cargando…
Distinct roles for major and minor antigen barriers in chimerism‐based tolerance under irradiation‐free conditions
Eliminating cytoreductive conditioning from chimerism‐based tolerance protocols would facilitate clinical translation. Here we investigated the impact of major histocompatibility complex (MHC) and minor histocompatibility antigen (MiHA) barriers on mechanisms of tolerance and rejection in this setti...
Autores principales: | Mahr, Benedikt, Pilat, Nina, Granofszky, Nicolas, Muckenhuber, Moritz, Unger, Lukas W., Weijler, Anna M., Wiletel, Mario, Steiner, Romy, Dorner, Lisa, Regele, Heinz, Wekerle, Thomas |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7984377/ https://www.ncbi.nlm.nih.gov/pubmed/32633070 http://dx.doi.org/10.1111/ajt.16177 |
Ejemplares similares
-
Anti-Interleukin-6 Promotes Allogeneic Bone Marrow Engraftment and Prolonged Graft Survival in an Irradiation-Free Murine Transplant Model
por: Granofszky, Nicolas, et al.
Publicado: (2017) -
Hybrid resistance to parental bone marrow grafts in nonlethally irradiated mice
por: Mahr, Benedikt, et al.
Publicado: (2018) -
Chronic CD40L blockade is required for long-term cardiac allograft survival with a clinically relevant CTLA4-Ig dosing regimen
por: Unger, Lukas W., et al.
Publicado: (2022) -
In vivo Treg expansion under costimulation blockade targets early rejection and improves long‐term outcome
por: Schwarz, Christoph, et al.
Publicado: (2021) -
Transplantation Tolerance through Hematopoietic Chimerism: Progress and Challenges for Clinical Translation
por: Mahr, Benedikt, et al.
Publicado: (2017)