Cargando…

Associations between TGF-β1 Levels and Markers of Hemolysis, Inflammation, and Tissue Remodeling in Pediatric Sickle Cell Patients

Transforming growth factor beta (TGF-β) is a cytokine with important involvement in biological processes related to the pathogenesis of sickle cell disease (SCD), including endothelial and vascular dysfunction, inflammation, and hematopoietic homeostasis. This study is aimed at investigating associa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Santiago, Rayra P., Carvalho, Magda O. S., Figueiredo, Camylla V. B., Fiuza, Luciana M., Oliveira, Rodrigo M., Yahouédéhou, Sètondji C. M. A., Nascimento, Valma M. L., Lyra, Isa M., Araujo-Santos, Théo, Luz, Nívea F., Aleluia, Milena M., Guarda, Caroline C., Borges, Valéria M., Goncalves, Marilda S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7984885/ https://www.ncbi.nlm.nih.gov/pubmed/33790690 http://dx.doi.org/10.1155/2021/4651891

Ejemplares similares

Hydroxyurea alters circulating monocyte subsets and dampens its inflammatory potential in sickle cell anemia patients
por: Guarda, Caroline C., et al.
Publicado: (2019)

Transforming Growth Factor Beta Receptor 3 Haplotypes in Sickle Cell Disease Are Associated with Lipid Profile and Clinical Manifestations
por: Santiago, Rayra P., et al.
Publicado: (2020)

TGFBR3 Polymorphisms (rs1805110 and rs7526590) Are Associated with Laboratory Biomarkers and Clinical Manifestations in Sickle Cell Anemia
por: Santiago, Rayra Pereira, et al.
Publicado: (2020)

Priapism in sickle cell disease: Associations between NOS3 and EDN1 genetic polymorphisms and laboratory biomarkers
por: Figueiredo, Camylla Vilas Boas, et al.
Publicado: (2021)

Sickle cell disease: A distinction of two most frequent genotypes (HbSS and HbSC)
por: da Guarda, Caroline Conceição, et al.
Publicado: (2020)

Hydroxyurea alters hematological, biochemical and inflammatory biomarkers in Brazilian children with SCA: Investigating associations with βS haplotype and α-thalassemia
por: Yahouédéhou, Sètondji Cocou Modeste Alexandre, et al.
Publicado: (2019)

Role of paraoxonase 1 activity and PON1 gene polymorphisms in sickle cell disease
por: Menezes, Joelma Figueiredo, et al.
Publicado: (2023)

Sickle Cell Anemia Patients in Use of Hydroxyurea: Association between Polymorphisms in Genes Encoding Metabolizing Drug Enzymes and Laboratory Parameters
por: Yahouédéhou, Sètondji Cocou Modeste Alexandre, et al.
Publicado: (2018)

Sickle Cell Anemia: Variants in the CYP2D6, CAT, and SLC14A1 Genes Are Associated With Improved Hydroxyurea Response
por: Yahouédéhou, Sètondji Cocou Modeste Alexandre, et al.
Publicado: (2020)

Investigation of Lipid Profile and Clinical Manifestations in SCA Children
por: da Guarda, Caroline Conceição, et al.
Publicado: (2020)

Association of laboratory markers and cerebral blood flow among sickle cell anemia children
por: Adanho, Corynne Stéphanie Ahouéfa, et al.
Publicado: (2022)

Leg Ulcers in Sickle Cell Disease: A Multifactorial Analysis Highlights the Hemolytic Profile
por: Santos, Edvan do Carmo, et al.
Publicado: (2023)

Genetic Polymorphisms Associated with Environmental Exposure to Polycyclic Derivatives in African Children
por: de Oliveira, Rodrigo Mota, et al.
Publicado: (2018)

Evaluation of Alpha-1 Antitrypsin Levels and SERPINA1 Gene Polymorphisms in Sickle Cell Disease
por: Carvalho, Magda Oliveira Seixas, et al.
Publicado: (2017)

A Description of the Hemolytic Component in Sickle Leg Ulcer: The Role of Circulating miR-199a-5p, miR-144, and miR-126
por: Santos, Edvan do Carmo, et al.
Publicado: (2022)

Laboratory and Genetic Biomarkers Associated with Cerebral Blood Flow Velocity in Hemoglobin SC Disease
por: Santiago, Rayra Pereira, et al.
Publicado: (2017)

Nasopharyngeal and Oropharyngeal Colonization by Staphylococcus aureus and Streptococcus pneumoniae and Prognostic Markers in Children with Sickle Cell Disease from the Northeast of Brazil
por: Rocha, Larissa C., et al.
Publicado: (2017)

Endothelial Nitric Oxide Synthase (−786T>C) and Endothelin-1 (5665G>T) Gene Polymorphisms as Vascular Dysfunction Risk Factors in Sickle Cell Anemia
por: Vilas-Boas, Wendell, et al.
Publicado: (2016)

Comparative study of sickle cell anemia and hemoglobin SC disease: clinical characterization, laboratory biomarkers and genetic profiles
por: Aleluia, Milena Magalhães, et al.
Publicado: (2017)

Effectiveness of Pharmacokinetic-Guided Hydroxyurea Dose Individualization in Patients with Sickle Cell Anemia: A Mini-Review
por: dos Santos Neres, Joelma Santana, et al.
Publicado: (2023)

Levels of high-density lipoprotein cholesterol (HDL-C) among children with steady-state sickle cell disease
por: Seixas, Magda O, et al.
Publicado: (2010)

Effect of N(Epsilon)-(carboxymethyl)lysine on Laboratory Parameters and Its Association with β(S) Haplotype in Children with Sickle Cell Anemia
por: Ndidi, Uche Samuel, et al.
Publicado: (2019)

Association of classical markers and establishment of the dyslipidemic sub-phenotype of sickle cell anemia
por: Aleluia, Milena Magalhães, et al.
Publicado: (2017)

Evaluation of Cardiometabolic Parameters among Obese Women Using Oral Contraceptives
por: Ferreira, Júnia Raquel Dutra, et al.
Publicado: (2017)

Prognostic value of the hemolysis index in patients with significant hemolysis
por: Cortés, Diego O, et al.
Publicado: (2015)

Sickle cell disease retinopathy: characterization among pediatric and teenage patients from northeastern Brazil
por: de Almeida Oliveira, Dayse Cury, et al.
Publicado: (2014)

Vaso‐occlusive crisis in a patient with sickle cell trait and COVID‐19
por: Freitas, Luiz A. R., et al.
Publicado: (2021)

Hydroxyurea Scavenges Free Radicals and Induces the Expression of Antioxidant Genes in Human Cell Cultures Treated With Hemin
por: Santana, Sânzio Silva, et al.
Publicado: (2020)

Fetal hemoglobin and hemolysis markers in sickle cell anemia()
por: Colella, Marina Pereira, et al.
Publicado: (2015)

Selenium Status and Hemolysis in Sickle Cell Disease Patients
por: Delesderrier, Emília, et al.
Publicado: (2019)

Doppler velocimetry of the orbital arteries in patients with sickle cell anemia: relationship with biomarkers of hemolysis
por: Ferrão, Thiago de Oliveira, et al.
Publicado: (2017)

Associations between endothelial dysfunction and clinical and laboratory parameters in children and adolescents with sickle cell anemia
por: Teixeira, Rozana Santos, et al.
Publicado: (2017)

Elevated Pulse Pressure is Associated with Hemolysis, Proteinuria and Chronic Kidney Disease in Sickle Cell Disease
por: Novelli, Enrico M., et al.
Publicado: (2014)

Albuminuria, serum antioxidant enzyme levels and markers of hemolysis and inflammation in steady state children with sickle cell anemia
por: Itokua, Karen E., et al.
Publicado: (2016)

Higher Rates of Hemolysis Are Not Associated with Albuminuria in Jamaicans with Sickle Cell Disease
por: Asnani, Monika R., et al.
Publicado: (2011)

The DAU Allele and Anti-D Alloimmunization Present With High Frequency in Brazilian Sickle Cell Disease Patients
por: de Moura Neto, Jose Pereira, et al.
Publicado: (2017)

Arginase levels and their association with Th17-related cytokines, soluble adhesion molecules (sICAM-1 and sVCAM-1) and hemolysis markers among steady-state sickle cell anemia patients
por: Vilas-Boas, Wendell, et al.
Publicado: (2010)

Sickle Cell Trait Increases Red Blood Cell Storage Hemolysis and Post-Transfusion Clearance in Mice
por: Osei-Hwedieh, David O., et al.
Publicado: (2016)

Evaluation of 2D and 3D Erythroid Differentiation Protocols Using Sickle Cell Disease and Healthy Donor Induced Pluripotent Stem Cells
por: Martins, Gabriele Louise Soares, et al.
Publicado: (2023)

Hemolysis During Hemodialysis
por: Sam, Ramin, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_2vojq8hogd980dhp0dago90vpf