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Decreased Expression of MPC2 Contributes to Aerobic Glycolysis and Colorectal Cancer Proliferation by Activating mTOR Pathway
Mitochondrial Pyruvate Carrier 1 (MPC1), one of the rate-limiting proteins involved in glycolysis metabolism, has been demonstrated as a tumor inhibitor in several cancers. This study was conducted with the aim of exploring the role and underlying mechanisms of MPC2 in colorectal cancer (CRC). Here,...
Autores principales: | Kuerbanjiang, Manzila, Gu, Lei, Xu, Chunjie, Xu, Wen Ting, Wen, Siyuan, Xue, Hanbing, Xu, Qing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7984920/ https://www.ncbi.nlm.nih.gov/pubmed/33791391 http://dx.doi.org/10.1155/2021/6618837 |
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