SUMOylation controls the binding of hexokinase 2 to mitochondria and protects against prostate cancer tumorigenesis

Human hexokinase 2 is an essential regulator of glycolysis that couples metabolic and proliferative activities in cancer cells. The binding of hexokinase 2 to the outer membrane of mitochondria is critical for its oncogenic activity. However, the regulation of hexokinase 2 binding to mitochondria re...

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Detalles Bibliográficos
Autores principales: Shangguan, Xun, He, Jianli, Ma, Zehua, zhang, Weiwei, Ji, Yiyi, Shen, Kai, Yue, Zhiying, Li, Wenyu, Xin, Zhixiang, Zheng, Quan, Cao, Ying, Pan, Jiahua, Dong, Baijun, Cheng, Jinke, Wang, Qi, Xue, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985146/
https://www.ncbi.nlm.nih.gov/pubmed/33753739
http://dx.doi.org/10.1038/s41467-021-22163-7

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