Cargando…

TMAO: a potential mediator of clopidogrel resistance

Trimethylamine-N-oxide (TMAO) can activate platelets and increase thrombosis risk in clinical and experimental models. Meanwhile, the patients with coronary artery disease have higher serum TMAO level. However, it remains unknown whether Clopidogrel Resistance (CR) could be attributed to TMAO. The p...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ma, Ruisong, Fu, Wenwen, Zhang, Jing, Hu, Xiaorong, Yang, Jun, Jiang, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985207/ https://www.ncbi.nlm.nih.gov/pubmed/33753834 http://dx.doi.org/10.1038/s41598-021-85950-8

Ejemplares similares

High Mobility Group Box 1 Mediates TMAO-Induced Endothelial Dysfunction
por: Singh, Gurinder Bir, et al.
Publicado: (2019)

The associations between TMAO-related metabolites and blood lipids and the potential impact of rosuvastatin therapy
por: Xiong, Xiaowei, et al.
Publicado: (2022)

Resveratrol Attenuates Trimethylamine-N-Oxide (TMAO)-Induced Atherosclerosis by Regulating TMAO Synthesis and Bile Acid Metabolism via Remodeling of the Gut Microbiota
por: Chen, Ming-liang, et al.
Publicado: (2016)

A Novel Multiplex HRM Assay to Detect Clopidogrel Resistance
por: Zhang, Lichen, et al.
Publicado: (2017)

Trimethylamine N-oxide (TMAO) in human health
por: Gatarek, Paulina, et al.
Publicado: (2021)

Aspirin and Clopidogrel Resistance
por: Sztriha, Laszlo K., et al.
Publicado: (2004)

Gut Microbiota Dysbiosis and Increased Plasma LPS and TMAO Levels in Patients With Preeclampsia
por: Wang, Jing, et al.
Publicado: (2019)

TMAO as a potential biomarker and therapeutic target for chronic kidney disease: A review
por: Zixin, Ye, et al.
Publicado: (2022)

Comparison of Clopidogrel and Ticlopidine/Ginkgo Biloba in Patients With Clopidogrel Resistance and Carotid Stenting
por: Chung, Jong-Won, et al.
Publicado: (2019)

Implication of Trimethylamine N-Oxide (TMAO) in Disease: Potential Biomarker or New Therapeutic Target
por: Janeiro, Manuel H., et al.
Publicado: (2018)

Trimethylamine-N-oxide (TMAO) as Novel Potential Biomarker of Early Predictors of Metabolic Syndrome
por: Barrea, Luigi, et al.
Publicado: (2018)

Clopidogrel induced arthritis and fever
por: Cao, Cheng-Fu, et al.
Publicado: (2017)

Background Diet Influences TMAO Concentrations Associated with Red Meat Intake without Influencing Apparent Hepatic TMAO-Related Activity in a Porcine Model
por: Thøgersen, Rebekka, et al.
Publicado: (2020)

Untargeted metabolomics and transcriptomics identified glutathione metabolism disturbance and PCS and TMAO as potential biomarkers for ER stress in lung
por: Wang, Zijing, et al.
Publicado: (2021)

TMAO promotes apoptosis and oxidative stress of pancreatic acinar cells by mediating IRE1α-XBP-1 pathway
por: Yang, Guodong, et al.
Publicado: (2021)

PRMT5 critically mediates TMAO-induced inflammatory response in vascular smooth muscle cells
por: Liu, He, et al.
Publicado: (2022)

Association between CYP2C19 and ABCB1 polymorphisms and clopidogrel resistance in clopidogrel-treated Chinese patients
por: Zhuo, Zhong-ling, et al.
Publicado: (2018)

Associations of PER3 polymorphisms with clopidogrel resistance among Chinese Han people treated with clopidogrel
por: Zheng, Nan, et al.
Publicado: (2021)

Mechanism of Prominent Trimethylamine Oxide (TMAO) Accumulation in Hemodialysis Patients
por: Hai, Xin, et al.
Publicado: (2015)

TMAO is Associated with Mortality: Impact of Modestly Impaired Renal Function
por: Gruppen, Eke G., et al.
Publicado: (2017)

DMSO and TMAO—Differences in Interactions in Aqueous Solutions of the K-Peptide
por: Godlewska, Julia, et al.
Publicado: (2022)

TMA, A Forgotten Uremic Toxin, but Not TMAO, Is Involved in Cardiovascular Pathology
por: Jaworska, Kinga, et al.
Publicado: (2019)

Modulation of Endothelial Function by TMAO, a Gut Microbiota-Derived Metabolite
por: Querio, Giulia, et al.
Publicado: (2023)

Gut-microbiota derived TMAO: A risk factor, a mediator or a bystander in the pathogenesis of atrial fibrillation?
por: Gawałko, Monika, et al.
Publicado: (2021)

Trimethylamine-N-oxide (TMAO) mediates the crosstalk between the gut microbiota and hepatic vascular niche to alleviate liver fibrosis in nonalcoholic steatohepatitis
por: Zhou, Dengcheng, et al.
Publicado: (2022)

Involvement of the DNA Phosphorothioation System in TorR Binding and Anaerobic TMAO Respiration in Salmonella enterica
por: Tang, You, et al.
Publicado: (2022)

Trimethylamine-N-oxide (TMAO)-induced atherosclerosis is associated with bile acid metabolism
por: Ding, Lin, et al.
Publicado: (2018)

Association of Urinary and Plasma Levels of Trimethylamine N-Oxide (TMAO) with Foods
por: Lombardo, Mauro, et al.
Publicado: (2021)

Association of the Chronotype Score with Circulating Trimethylamine N-Oxide (TMAO) Concentrations
por: Barrea, Luigi, et al.
Publicado: (2021)

Contribution of Trimethylamine N-Oxide (TMAO) to Chronic Inflammatory and Degenerative Diseases
por: Constantino-Jonapa, Luis A., et al.
Publicado: (2023)

The Protective Role of Interleukin-33 in Myocardial Ischemia and Reperfusion Is Associated with Decreased HMGB1 Expression and Up-Regulation of the P38 MAPK Signaling Pathway
por: Ruisong, Ma, et al.
Publicado: (2015)

Trimethylamine N-Oxide (TMAO) Inducing Endothelial Injury: UPLC-MS/MS-Based Quantification and the Activation of Cathepsin B-Mediated NLRP3 Inflammasome
por: Lei, Dongyu, et al.
Publicado: (2023)

Inhibition of autophagy via activation of PI3K/Akt/mTOR pathway contributes to the protection of hesperidin against myocardial ischemia/reperfusion injury
por: Li, Xuefei, et al.
Publicado: (2018)

Gut Microbiota-Dependent Marker TMAO in Promoting Cardiovascular Disease: Inflammation Mechanism, Clinical Prognostic, and Potential as a Therapeutic Target
por: Yang, Shengjie, et al.
Publicado: (2019)

TMAO-Activated Hepatocyte-Derived Exosomes Impair Angiogenesis via Repressing CXCR4
por: Liu, Xiang, et al.
Publicado: (2022)

Inhibition of microbiota-dependent TMAO production attenuates chronic kidney disease in mice
por: Zhang, Wenchao, et al.
Publicado: (2021)

Comment on “Association between CYP2C19 and ABCB1 polymorphisms and clopidogrel resistance in clopidogrel-treated Chinese patients”
por: Wang, Bin, et al.
Publicado: (2018)

Association Between Frailty and Gut Microbiota Metabolite TMAO in Older People With Cardiovascular Disease
por: He, Wei, et al.
Publicado: (2020)

Gut-Derived Metabolite, Trimethylamine-N-oxide (TMAO) in Cardio-Metabolic Diseases: Detection, Mechanism, and Potential Therapeutics
por: Shanmugham, Meyammai, et al.
Publicado: (2023)

Berberine treats atherosclerosis via a vitamine-like effect down-regulating Choline-TMA-TMAO production pathway in gut microbiota
por: Ma, Shu-Rong, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_jsrkeihagcd55vv112l45pru19