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The origins and genetic interactions of KRAS mutations are allele- and tissue-specific

Mutational activation of KRAS promotes the initiation and progression of cancers, especially in the colorectum, pancreas, lung, and blood plasma, with varying prevalence of specific activating missense mutations. Although epidemiological studies connect specific alleles to clinical outcomes, the mec...

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Detalles Bibliográficos
Autores principales:	Cook, Joshua H., Melloni, Giorgio E. M., Gulhan, Doga C., Park, Peter J., Haigis, Kevin M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985210/ https://www.ncbi.nlm.nih.gov/pubmed/33753749 http://dx.doi.org/10.1038/s41467-021-22125-z

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