Nongenotoxic ABCB1 activator tetraphenylphosphonium can contribute to doxorubicin resistance in MX-1 breast cancer cell line

Hyperactivation of ABC transporter ABCB1 and induction of epithelial–mesenchymal transition (EMT) are the most common mechanism of acquired cancer chemoresistance. This study describes possible mechanisms, that might contribute to upregulation of ABCB1 and synergistically boost the acquisition of do...

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Detalles Bibliográficos
Autores principales: Kubiliute, Raimonda, Januskeviciene, Indre, Urbanaviciute, Ruta, Daniunaite, Kristina, Drobniene, Monika, Ostapenko, Valerijus, Daugelavicius, Rimantas, Jarmalaite, Sonata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985213/
https://www.ncbi.nlm.nih.gov/pubmed/33753859
http://dx.doi.org/10.1038/s41598-021-86120-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985213/
https://www.ncbi.nlm.nih.gov/pubmed/33753859
http://dx.doi.org/10.1038/s41598-021-86120-6

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