Structural insights into SARS-CoV-2 infection and therapeutics development

The current COVID-19 pandemic is caused by the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2). By late October 2020, more than 43 million cases of infections, including over 1.15 million deaths, have been confirmed worldwide. This review focuses on our current understanding of SARS-CoV...

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Detalles Bibliográficos
Autores principales: Sun, Gangyu, Xue, Lulu, He, Qingjing, Zhao, Yue, Xu, Wenqing, Wang, Zhizhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier B.V. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985237/
https://www.ncbi.nlm.nih.gov/pubmed/33550140
http://dx.doi.org/10.1016/j.scr.2021.102219
Descripción
Sumario:The current COVID-19 pandemic is caused by the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2). By late October 2020, more than 43 million cases of infections, including over 1.15 million deaths, have been confirmed worldwide. This review focuses on our current understanding of SARS-CoV-2 from the perspective of the three-dimensional (3D) structures of SARS-CoV-2 viral proteins and their implications on therapeutics development against COVID-19.

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