New insight of immuno-engineering in osteoimmunomodulation for bone regeneration

With the continuous development of bone tissue engineering, the importance of immune response in bone tissue regeneration is gradually recognized. The new bone tissue engineering products should possess immunoregulatory functions, harmonizing the interactions between the bone's immune defense a...

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Detalles Bibliográficos
Autores principales: Ouyang, Long, Cao, Jiankun, Dai, Qiang, Qiu, Daojing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society for Regenerative Medicine 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985270/
https://www.ncbi.nlm.nih.gov/pubmed/33778136
http://dx.doi.org/10.1016/j.reth.2021.03.003
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author Ouyang, Long
Cao, Jiankun
Dai, Qiang
Qiu, Daojing
author_facet Ouyang, Long
Cao, Jiankun
Dai, Qiang
Qiu, Daojing
author_sort Ouyang, Long
collection PubMed
description With the continuous development of bone tissue engineering, the importance of immune response in bone tissue regeneration is gradually recognized. The new bone tissue engineering products should possess immunoregulatory functions, harmonizing the interactions between the bone's immune defense and regeneration systems, and promoting tissue regeneration. This article will interpret the relationship between the bone immune system, bone tissue regeneration, as well as the immunoregulatory function of bone biomaterials and seed stem cells in bone tissue engineering. This review locates arears for foucusing efforts at providing novel designs ideas about the development of immune-mediation targeted bone tissue engineering products and the evaluation strategy for the osteoimmunomodulation property of bone biomaterials.
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spelling pubmed-79852702021-03-25 New insight of immuno-engineering in osteoimmunomodulation for bone regeneration Ouyang, Long Cao, Jiankun Dai, Qiang Qiu, Daojing Regen Ther Review With the continuous development of bone tissue engineering, the importance of immune response in bone tissue regeneration is gradually recognized. The new bone tissue engineering products should possess immunoregulatory functions, harmonizing the interactions between the bone's immune defense and regeneration systems, and promoting tissue regeneration. This article will interpret the relationship between the bone immune system, bone tissue regeneration, as well as the immunoregulatory function of bone biomaterials and seed stem cells in bone tissue engineering. This review locates arears for foucusing efforts at providing novel designs ideas about the development of immune-mediation targeted bone tissue engineering products and the evaluation strategy for the osteoimmunomodulation property of bone biomaterials. Japanese Society for Regenerative Medicine 2021-03-19 /pmc/articles/PMC7985270/ /pubmed/33778136 http://dx.doi.org/10.1016/j.reth.2021.03.003 Text en © 2021 The Japanese Society for Regenerative Medicine. Production and hosting by Elsevier B.V. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review
Ouyang, Long
Cao, Jiankun
Dai, Qiang
Qiu, Daojing
New insight of immuno-engineering in osteoimmunomodulation for bone regeneration
title New insight of immuno-engineering in osteoimmunomodulation for bone regeneration
title_full New insight of immuno-engineering in osteoimmunomodulation for bone regeneration
title_fullStr New insight of immuno-engineering in osteoimmunomodulation for bone regeneration
title_full_unstemmed New insight of immuno-engineering in osteoimmunomodulation for bone regeneration
title_short New insight of immuno-engineering in osteoimmunomodulation for bone regeneration
title_sort new insight of immuno-engineering in osteoimmunomodulation for bone regeneration
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985270/
https://www.ncbi.nlm.nih.gov/pubmed/33778136
http://dx.doi.org/10.1016/j.reth.2021.03.003
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AT qiudaojing newinsightofimmunoengineeringinosteoimmunomodulationforboneregeneration

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