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Single dose of a replication-defective vaccinia virus expressing Zika virus-like particles is protective in mice

Zika virus (ZIKV), a flavivirus transmitted primarily by infected mosquitos, can cause neurological symptoms such as Guillian–Barré syndrome and microcephaly. We developed several vaccinia virus (VACV) vaccine candidates for ZIKV based on replication-inducible VACVs (vINDs) expressing ZIKV pre-membr...

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Detalles Bibliográficos
Autores principales:	Jasperse, Brittany, O’Connell, Caitlin M., Wang, Yuxiang, Verardi, Paulo H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985303/ https://www.ncbi.nlm.nih.gov/pubmed/33753816 http://dx.doi.org/10.1038/s41598-021-85951-7

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