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FGF21 facilitates autophagy in prostate cancer cells by inhibiting the PI3K–Akt–mTOR signaling pathway

Fibroblast growth factor 21 (FGF21) plays an important role in regulating glucose and lipid metabolism, but its role in cancer is less well-studied. We aimed to investigate the action of FGF21 in the development of prostate cancer (PCa). Herein, we found that FGF21 expression was markedly downregula...

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Detalles Bibliográficos
Autores principales: Dai, Han, Hu, Wenjing, Zhang, Lianying, Jiang, Feiyu, Mao, Xiongmin, Yang, Gangyi, Li, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985321/
https://www.ncbi.nlm.nih.gov/pubmed/33753729
http://dx.doi.org/10.1038/s41419-021-03588-w

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