Cancer imaging and therapy utilizing a novel NIS-expressing adenovirus: The role of adenovirus death protein deletion

Encoding the sodium iodide symporter (NIS) by an adenovirus (Ad) is a promising strategy to facilitate non-invasive imaging and radiotherapy of pancreatic cancer. However, insufficient levels of NIS expression in tumor cells have limited its clinical translation. To optimize Ad-based radiotherapy an...

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Detalles Bibliográficos
Autores principales: Robertson, Matthew Glen, Eidenschink, Benjamin Bruce, Iguchi, Eriko, Zakharkin, Stanislav O., LaRocca, Christopher J., Tolosa, Ezequiel J., Truty, Mark J., Jacobsen, Kari, Fernandez-Zapico, Martin E., Davydova, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985464/
https://www.ncbi.nlm.nih.gov/pubmed/33816784
http://dx.doi.org/10.1016/j.omto.2021.03.002

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